Celecoxib nanocrystal-loaded dissolving microneedles with highly efficient for osteoarthritis treatment

Q Wang, X Yang, X Gu, F Wei, W Cao, L Zheng… - International Journal of …, 2022 - Elsevier
Osteoarthritis (OA) is a prevalent degenerative disease that has a significant impact on
patients' lives. Celecoxib (CXB) is now primarily used to treat OA with oral dosing. CXB's …

Association between interleukin-17A/F single nucleotide polymorphisms and susceptibility to osteoarthritis in a Chinese population

L Jiang, X Zhou, Y Xiong, J Bao, K Xu, L Wu - Medicine, 2019 - journals.lww.com
Abstract Interleukin-17A/F (IL-17A/F) might play a role in the pathophysiology of
osteoarthritis (OA), but several studies exploring the association between IL-17A/F single …

Genetic association scan of 32 osteoarthritis susceptibility genes identified TP63 associated with an endemic osteoarthritis, Kashin-Beck disease

B Cheng, C Liang, X Yang, P Li, L Liu, S Cheng, Y Jia… - Bone, 2021 - Elsevier
Abstract Background Kashin-Beck disease (KBD) is an endemic chronic osteochondropathy.
The clinical manifestations and radiographic features of adult KBD were similar to those of …

[PDF][PDF] The polymorphism of matrilin-3 (rs77245812) and interleukin-10 (rs1800872) genes in osteoarthritis patients with arterial hypertension, obesity and type 2 …

LP Sydorchuk, YI Serdulets, AR Sydorchuk… - Arch Balk Med …, 2017 - umbalk.org
Introduction. Osteoarthritis (OA) is a multifactorial disorder in which ageing, genetic,
hormonal and mechanical factors are major contributors to its onset and progression …

Interaction between GDF5 gene polymorphisms and environment factors increased the risk of knee osteoarthritis: a case–control study

S Zhang, J Wang, H Ji, H Jia, D Guan - Bioscience Reports, 2019 - portlandpress.com
Using a case–control design, we assessed the association between single nucleotide
polymorphisms (SNPs) of growth and differentiation factor 5 (GDF5)/rs143383 gene and …

Investigation of lncRNA PART1 SNP (rs8176070) polymorphism in Turkey knee osteoarthritis patient population by DNA sequence analysis

I Piskin, G Akcan, A Firat, AC Tufan - Human Gene, 2023 - Elsevier
Osteoarthritis (OA) is a chronic disease characterised by cartilage degradation, synovial
inflammation, subchondral bone remodelling, and osteophyte formation. The aim of this …

3′-UTR Polymorphisms of MTHFR and TS Associated with Osteoporotic Vertebral Compression Fracture Susceptibility in Postmenopausal Women

TK Ahn, JO Kim, HW Kim, HS Park, JH Shim… - International journal of …, 2018 - mdpi.com
Postmenopausal osteoporosis is one of the most prominent diseases in postmenopausal
women and it is increasing in prevalence with the aging population. Furthermore …

Analysis of Polymorphisms in the MATN3 and DOT1L Genes and CTX-II Urinary Levels in Patients with Knee Osteoarthritis in a Northeast Mexican-Mestizo …

FJ García-Alvarado, HA Delgado-Aguirre… - Genetic Testing and …, 2020 - liebertpub.com
Aims: To investigate the possible roles of the single nucleotide polymorphisms (SNPs)
MATN3 (rs77245812) and DOT1L (rs12982744) with susceptibility to knee osteoarthritis …

[HTML][HTML] Association between MATN-3 gene polymorphism and primary knee osteoarthritis in indian population: a community-based case-control study

V Trivedi, R Shah, S Qidwai, M AN, T Raza… - Fortune Journal of …, 2020 - fortuneonline.org
Background and objectives: In the occurrence and development of primary knee
osteoarthritis, the potential role of genetic factor has become an attraction for researches …

[PDF][PDF] IL-1 茁基因多态性与新疆维吾尔族原发性膝骨关节炎发病的关系研究

刘振峰, 梁治权, 艾力江, 阿斯拉, 方锐, 邓迎杰… - biomed.cnjournals.com
摘要目的: 研究白细胞介素-1 茁(IL-1 茁) 基因多态性与新疆维吾尔族原发性膝骨关节炎(PKOA)
发病的关系. 方法: 选择从2015 年9 月到2017 年8 月在我院就诊的新疆维吾尔族PKOA 患者50 …