Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine

ND Donahue, H Acar, S Wilhelm - Advanced drug delivery reviews, 2019 - Elsevier
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

Degradability and clearance of silicon, organosilica, silsesquioxane, silica mixed oxide, and mesoporous silica nanoparticles

JG Croissant, Y Fatieiev, NM Khashab - Advanced materials, 2017 - Wiley Online Library
The biorelated degradability and clearance of siliceous nanomaterials have been
questioned worldwide, since they are crucial prerequisites for the successful translation in …

Antimicrobial photodynamic therapy: Latest developments with a focus on combinatory strategies

R Youf, M Müller, A Balasini, F Thétiot, M Müller… - Pharmaceutics, 2021 - mdpi.com
Antimicrobial photodynamic therapy (aPDT) has become a fundamental tool in modern
therapeutics, notably due to the expanding versatility of photosensitizers (PSs) and the …

Tailoring porous silicon for biomedical applications: from drug delivery to cancer immunotherapy

W Li, Z Liu, F Fontana, Y Ding, D Liu… - Advanced …, 2018 - Wiley Online Library
In the past two decades, porous silicon (PSi) has attracted increasing attention for its
potential biomedical applications. With its controllable geometry, tunable nanoporous …

Emerging applications of porphyrins in photomedicine

H Huang, W Song, J Rieffel, JF Lovell - Frontiers in physics, 2015 - frontiersin.org
Biomedical applications of porphyrins and related molecules have been extensively
pursued in the context of photodynamic therapy. Recent advances in nanoscale engineering …

Photodynamic therapy: Inception to application in breast cancer

SM Banerjee, AJ MacRobert, CA Mosse, B Periera… - The Breast, 2017 - Elsevier
Photodynamic therapy (PDT) is already being used in the treatment of many cancers. This
review examines its components and the new developments in our understanding of its …

Image-guided combination chemotherapy and photodynamic therapy using a mitochondria-targeted molecular probe with aggregation-induced emission …

CJ Zhang, Q Hu, G Feng, R Zhang, Y Yuan, X Lu… - Chemical …, 2015 - pubs.rsc.org
Subcellular targeted cancer therapy and in situ monitoring of therapeutic effect are highly
desirable for clinical applications. Herein, we report a series of probes by conjugating zero …

[PDF][PDF] Two-photon excitation of porphyrin-functionalized porous silicon nanoparticles for photodynamic therapy

E Secret, M Maynadier, A Gallud, A Chaix, E Bouffard… - Adv. Mater, 2014 - academia.edu
Nanomaterials offer the potential for minimally invasive and focal therapies to reduce side-
effects associated with systemic administration of anticancer drugs. Clinical treatment …

Silicon nanoparticles: Preparation, properties, and applications

H Chang, SQ Sun - Chinese Physics B, 2014 - iopscience.iop.org
Silicon nanoparticles have attracted great attention in the past decades because of their
intriguing physical properties, active surface state, distinctive photoluminescence and …

Photodynamic therapy activity of new porphyrin-xylan-coated silica nanoparticles in human colorectal cancer

L Bretin, A Pinon, S Bouramtane, C Ouk, L Richard… - Cancers, 2019 - mdpi.com
Photodynamic therapy (PDT) using porphyrins has been approved for treatment of several
solid tumors due to the generation of cytotoxic reactive oxygen species (ROS). However, low …