How bacteria use type IV pili machinery on surfaces

B Maier, GCL Wong - Trends in microbiology, 2015 - cell.com
The bacterial type IV pilus (T4P) is a versatile molecular machine with a broad range of
functions. Recent advances revealed that the molecular components and the biophysical …

Regulation of Cell Polarity in Motility and Cell Division in Myxococcus xanthus

D Schumacher… - Annual review of …, 2017 - annualreviews.org
Rod-shaped Myxococcus xanthus cells are polarized with proteins asymmetrically localizing
to specific positions. This spatial organization is important for regulation of motility and cell …

Architecture of the type IVa pilus machine

YW Chang, L Rettberg, A Treuner-Lange, J Iwasa… - Biophysical …, 2016 - cell.com
Type IV pili are part of a widespread superfamily of bacterial and archaeal cell surface
structures important for biofilm formation, motility, host adhesion, predation, DNA uptake …

[HTML][HTML] ParB-type DNA segregation proteins are CTP-dependent molecular switches

M Osorio-Valeriano, F Altegoer, W Steinchen, S Urban… - Cell, 2019 - cell.com
During cell division, newly replicated DNA is actively segregated to the daughter cells. In
most bacteria, this process involves the DNA-binding protein ParB, which condenses the …

Halofilins as emerging bactofilin families of archaeal cell shape plasticity orchestrators

Z Curtis, P Escudeiro, J Mallon, O Leland… - Proceedings of the …, 2024 - pnas.org
Bactofilins are rigid, nonpolar bacterial cytoskeletal filaments that link cellular processes to
specific curvatures of the cytoplasmic membrane. Although homologs of bactofilins have …

Interaction of the cyclic-di-GMP binding protein FimX and the Type 4 pilus assembly ATPase promotes pilus assembly

R Jain, O Sliusarenko, BI Kazmierczak - PLoS pathogens, 2017 - journals.plos.org
Type IVa pili (T4P) are bacterial surface structures that enable motility, adhesion, biofilm
formation and virulence. T4P are assembled by nanomachines that span the bacterial cell …

Bacterial twitching motility is coordinated by a two-dimensional tug-of-war with directional memory

R Marathe, C Meel, NC Schmidt, L Dewenter… - Nature …, 2014 - nature.com
Type IV pili are ubiquitous bacterial motors that power surface motility. In peritrichously
piliated species, it is unclear how multiple pili are coordinated to generate movement with …

Regulation of cell polarity in bacteria

A Treuner-Lange, L Søgaard-Andersen - Journal of Cell Biology, 2014 - rupress.org
Bacteria are polarized cells with many asymmetrically localized proteins that are regulated
temporally and spatially. This spatiotemporal dynamics is critical for several fundamental …

Outside-in assembly pathway of the type IV pilus system in Myxococcus xanthus

C Friedrich, I Bulyha… - Journal of bacteriology, 2014 - Am Soc Microbiol
ABSTRACT Type IV pili (T4P) are ubiquitous bacterial cell surface structures that undergo
cycles of extension, adhesion, and retraction. T4P function depends on a highly conserved …

Bactofilin-mediated organization of the ParABS chromosome segregation system in Myxococcus xanthus

L Lin, M Osorio Valeriano, A Harms… - Nature …, 2017 - nature.com
In bacteria, homologs of actin, tubulin, and intermediate filament proteins often act in concert
with bacteria-specific scaffolding proteins to ensure the proper arrangement of cellular …