Fetuin-A: a multifunctional protein

K Mori, M Emoto, M Inaba - Recent patents on endocrine …, 2011 - ingentaconnect.com
Sixty-six years have elapsed since the discovery of fetuin in 1944, but its importance in
mammalian physiology has only recently been appreciated. Fetuin, first isolated from fetal …

Clinical implications of fetuin-A

P Jirak, L Stechemesser, E Moré, M Franzen… - Advances in clinical …, 2019 - Elsevier
Fetuin-A, also termed alpha2-Heremans-Schmid glycoprotein, is a 46 kDa hepatocyte
derived protein (hepatokine) and serves multifaceted functions.(i) It acts as systemic inhibitor …

Effects of pioglitazone on serum fetuin-A levels in patients with type 2 diabetes mellitus

K Mori, M Emoto, T Araki, H Yokoyama, E Lee… - Metabolism, 2008 - Elsevier
Fetuin-A (α2-Heremans-Schmid glycoprotein), a circulating glycoprotein, can inhibit insulin
signaling both in vivo and in vitro. Recently, we and another independent group have shown …

Plasma fetuin‐A is associated with endothelial dysfunction and subclinical atherosclerosis in subjects with nonalcoholic fatty liver disease

T Dogru, H Genc, S Tapan, F Aslan… - Clinical …, 2013 - Wiley Online Library
Objective Nonalcoholic fatty liver disease (NAFLD), a hepatic manifestation of metabolic
syndrome (M et S) is closely associated with an increased risk of cardiovascular disease …

Association of AHSG Gene Polymorphisms With Fetuin-A Plasma Levels and Cardiovascular Diseases in the EPIC-Potsdam Study

E Fisher, N Stefan, K Saar, D Drogan… - Circulation …, 2009 - Am Heart Assoc
Background—Elevated circulating levels of fetuin-A in blood have been associated with
increased risk of cardiovascular disease. The goal of our study was to prospectively …

[HTML][HTML] The role of fetuin-A in mineral trafficking and deposition

MMX Cai, ER Smith, SG Holt - BoneKEy reports, 2015 - ncbi.nlm.nih.gov
Calcium and phosphate are the principle ions involved in the deposition of mineral in the
human body. Inhibitors of mineralisation are essential for the prevention of ectopic mineral …

Fetuin-A and the cardiovascular system

K Mori, M Emoto, M Inaba - Advances in clinical chemistry, 2012 - books.google.com
Fetuin was first isolated from bovine serum in 1944. It is now most commonly known as
either fetuin-A or alpha-2-HS-glycoprotein (AHSG), the protein product of Ahsg gene. A …

Vascular calcification and fetuin-A deficiency in chronic kidney disease

R Westenfeld, W Jahnen-Dechent, M Ketteler - Trends in cardiovascular …, 2007 - Elsevier
In past decades, extraosseous (including cardiovascular) calcification was predominantly
regarded as a passive process of limited pathophysiological significance. It was thought that …

[HTML][HTML] Mineralisation of soft and hard tissues and the stability of biofluids

C Holt, S Lenton, T Nylander, ES Sørensen… - Journal of structural …, 2014 - Elsevier
Evidence is provided from studies on natural and artificial biofluids that the sequestration of
amorphous calcium phosphate by peptides or proteins to form nanocluster complexes is of …

The effects of caloric restriction on F etuin‐A and cardiovascular risk factors in rats and humans: a randomized controlled trial

KM Choi, KA Han, HJ Ahn, SY Lee… - Clinical …, 2013 - Wiley Online Library
Objectives The liver‐secreted protein fetuin‐A is associated with insulin resistance,
metabolic syndrome, type 2 diabetes and atherosclerosis. We examined the effect of caloric …