Restoring sensorimotor function through intracortical interfaces: progress and looming challenges

SJ Bensmaia, LE Miller - Nature Reviews Neuroscience, 2014 - nature.com
The loss of a limb or paralysis resulting from spinal cord injury has devastating
consequences on quality of life. One approach to restoring lost sensory and motor abilities in …

Neural interfaces for somatosensory feedback: bringing life to a prosthesis

DJ Tyler - Current opinion in neurology, 2015 - journals.lww.com
Neural interfaces with sophisticated stimulation paradigms create a user's perception of
his/her hand to touch and manipulate objects. The pattern of intensity and frequency of …

Characterization of evoked tactile sensation in forearm amputees with transcutaneous electrical nerve stimulation

G Chai, X Sui, S Li, L He, N Lan - Journal of neural engineering, 2015 - iopscience.iop.org
Objective. The goal of this study is to characterize the phenomenon of evoked tactile
sensation (ETS) on the stump skin of forearm amputees using transcutaneous electrical …

Multimodal interactions between proprioceptive and cutaneous signals in primary somatosensory cortex

SS Kim, M Gomez-Ramirez, PH Thakur, SS Hsiao - Neuron, 2015 - cell.com
The classical view of somatosensory processing holds that proprioceptive and cutaneous
inputs are conveyed to cortex through segregated channels, initially synapsing in modality …

Selectivity and longevity of peripheral-nerve and machine interfaces: a review

U Ghafoor, S Kim, KS Hong - Frontiers in Neurorobotics, 2017 - frontiersin.org
For those individuals with upper-extremity amputation, a daily normal living activity is no
longer possible or it requires additional effort and time. With the aim of restoring their …

Responses of somatosensory area 2 neurons to actively and passively generated limb movements

BM London, LE Miller - Journal of neurophysiology, 2013 - journals.physiology.org
Control of reaching movements requires an accurate estimate of the state of the limb, yet
sensory signals are inherently noisy, because of both noise at the receptors themselves and …

[HTML][HTML] The challenge of understanding the brain: where we stand in 2015

J Lisman - Neuron, 2015 - cell.com
Starting with the work of Cajal more than 100 years ago, neuroscience has sought to
understand how the cells of the brain give rise to cognitive functions. How far has …

Area 2 of primary somatosensory cortex encodes kinematics of the whole arm

RH Chowdhury, JI Glaser, LE Miller - Elife, 2020 - elifesciences.org
Proprioception, the sense of body position, movement, and associated forces, remains
poorly understood, despite its critical role in movement. Most studies of area 2, a …

Temporal pattern of electrical stimulation is a new dimension of therapeutic innovation

WM Grill - Current opinion in biomedical engineering, 2018 - Elsevier
Artificial activation of the nervous system requires selection of appropriate stimulation
parameters including stimulation amplitude, stimulation pulse duration, and stimulation …

Characterizing the short-latency evoked response to intracortical microstimulation across a multi-electrode array

JT Sombeck, J Heye, K Kumaravelu… - Journal of Neural …, 2022 - iopscience.iop.org
Objective. Persons with tetraplegia can use brain-machine interfaces to make visually
guided reaches with robotic arms. Without somatosensory feedback, these movements will …