Industrial applications of enzyme biocatalysis: Current status and future aspects

JM Choi, SS Han, HS Kim - Biotechnology advances, 2015 - Elsevier
Enzymes are the most proficient catalysts, offering much more competitive processes
compared to chemical catalysts. The number of industrial applications for enzymes has …

Enzyme engineering and its industrial applications

I Victorino da Silva Amatto… - Biotechnology and …, 2022 - Wiley Online Library
Recently, there has been an increase in the demand for enzymes with modified activity,
specificity, and stability. Enzyme engineering is an important tool to meet the demand for …

From directed evolution to computational enzyme engineering—a review

R Chowdhury, CD Maranas - AIChE Journal, 2020 - Wiley Online Library
Nature relies on a wide range of enzymes with specific biocatalytic roles to carry out much of
the chemistry needed to sustain life. Enzymes catalyze the interconversion of a vast array of …

Application of designed enzymes in organic synthesis

GA Strohmeier, H Pichler, O May… - Chemical …, 2011 - ACS Publications
Catalysis is a key discipline in chemistry enabling clean and cost-efficient processes for a
large variety of different products and, therefore, has a strong economic impact in industry …

Protein engineering of microbial enzymes

D Böttcher, UT Bornscheuer - Current opinion in microbiology, 2010 - Elsevier
Protein engineering has emerged as an important tool to overcome the limitations of natural
enzymes as biocatalysts. Recent advances have mainly focused on applying directed …

Nature-inspired Enzyme engineering and sustainable catalysis: biochemical clues from the world of plants and extremophiles

A Chatterjee, S Puri, PK Sharma, PR Deepa… - … in Bioengineering and …, 2023 - frontiersin.org
The use of enzymes to accelerate chemical reactions for the synthesis of industrially
important products is rapidly gaining popularity. Biocatalysis is an environment-friendly …

Engineering of Candida antarctica lipase B for hydrolysis of bulky carboxylic acid esters

PB Juhl, K Doderer, F Hollmann, O Thum… - Journal of biotechnology, 2010 - Elsevier
Candida antarctica lipase B (CALB) is a widely used biocatalyst with high activity and
specificity for a wide range of primary and secondary alcohols. However, the range of …

Protein design in metabolic engineering and synthetic biology

J Pleiss - Current opinion in biotechnology, 2011 - Elsevier
Starting from experimental data on sequence, structure or biochemical properties of
enzymes, protein design seeks to construct enzymes with desired activity, stability, specificity …

Improving D-carbamoylase thermostability through salt bridge engineering for efficient D-p-hydroxyphenylglycine production

L Zhang, C Gao, W Song, W Wei, C Gao… - Systems Microbiology …, 2024 - Springer
Abstract Dp-hydroxyphenylglycine (D-HPG) is an important intermediate in the
pharmaceutical industry, and it is commonly synthesized by cascading D-hydantoinase …

Structure-guided rational design of the substrate specificity and catalytic activity of an enzyme

JM Choi, HS Kim - Methods in Enzymology, 2020 - Elsevier
The quest for an enzyme with desired property is high for biocatalyic production of valuable
products in industrial biotechnology. Synthetic biology and metabolic engineering also …