Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
Therapeutic and diagnostic translation of extracellular vesicles in cardiovascular diseases: roadmap to the clinic
S Sahoo, M Adamiak, P Mathiyalagan, F Kenneweg… - Circulation, 2021 - Am Heart Assoc
Exosomes are small membrane-bound vesicles of endocytic origin that are actively
secreted. The potential of exosomes as effective communicators of biological signaling in …
secreted. The potential of exosomes as effective communicators of biological signaling in …
Atorvastatin enhances the therapeutic efficacy of mesenchymal stem cells-derived exosomes in acute myocardial infarction via up-regulating long non-coding RNA …
P Huang, L Wang, Q Li, X Tian, J Xu, J Xu… - Cardiovascular …, 2020 - academic.oup.com
Aims Naturally secreted nanovesicles, known as exosomes, play important roles in stem cell-
mediated cardioprotection. We have previously demonstrated that atorvastatin (ATV) …
mediated cardioprotection. We have previously demonstrated that atorvastatin (ATV) …
[HTML][HTML] The implications of exosomes in pregnancy: emerging as new diagnostic markers and therapeutics targets
Extracellular vehicles (EVs) are a heterogeneous group of cell and membranous particles
originating from different cell compartments. EVs participate in many essential physiological …
originating from different cell compartments. EVs participate in many essential physiological …
[HTML][HTML] Combinatorial treatment of acute myocardial infarction using stem cells and their derived exosomes resulted in improved heart performance
P Huang, L Wang, Q Li, J Xu, J Xu, Y Xiong… - Stem cell research & …, 2019 - Springer
Background Bone marrow mesenchymal stem cells (MSCs) are among the most common
cell types to be used and studied for cardiac regeneration. Low survival rate and difficult …
cell types to be used and studied for cardiac regeneration. Low survival rate and difficult …
[HTML][HTML] Exosome in cardiovascular diseases: a complex world full of hope
G Bellin, C Gardin, L Ferroni, JC Chachques… - Cells, 2019 - mdpi.com
Exosomes are a subgroup of extracellular vesicles containing a huge number of bioactive
molecules. They represent an important means of cell communication, mostly between …
molecules. They represent an important means of cell communication, mostly between …
Advances in injectable hydrogel strategies for heart failure treatment
Heart failure (HF) affects 60 million people worldwide and has developed into a global
public health problem surpassing cancer and urgently needs to be solved. According to the …
public health problem surpassing cancer and urgently needs to be solved. According to the …
[HTML][HTML] Adipose tissue stem cells in regenerative medicine
VV Miana, EAP González - Ecancermedicalscience, 2018 - ncbi.nlm.nih.gov
Adipose tissue-derived stem cells (ADSCs) are mesenchymal cells with the capacity for self-
renewal and multipotential differentiation. This multipotentiality allows them to become …
renewal and multipotential differentiation. This multipotentiality allows them to become …
[HTML][HTML] Extracellular vesicles in cardiovascular diseases: alternative biomarker sources, therapeutic agents, and drug delivery carriers
Cardiovascular diseases (CVD) represent the leading cause of morbidity and mortality
globally. The emerging role of extracellular vesicles (EVs) in intercellular communication …
globally. The emerging role of extracellular vesicles (EVs) in intercellular communication …
[HTML][HTML] Exosomes in myocardial repair: advances and challenges in the development of next-generation therapeutics
M Adamiak, S Sahoo - Molecular Therapy, 2018 - cell.com
Myocardial disease is a leading cause of morbidity and mortality worldwide. Given the
limited regenerative capacity of the human heart following myocardial injury, stem cell …
limited regenerative capacity of the human heart following myocardial injury, stem cell …