Aging is a natural process that is associated with cognitive decline as well as functional and
social impairments. One structure of particular interest when considering aging and …

Brain‐derived neurotrophic factor (BDNF) is a neurotrophin that is vital to the survival,
growth, and maintenance of neurons in key brain circuits involved in emotional and …

Major depressive disorder (MDD) will affect one out of every five people in their lifetime and
is the leading cause of disability worldwide. Nevertheless, mechanisms associated with the …

Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …

Age-related cognitive changes often include difficulties in retrieving memories, particularly
those that rely on personal experiences within their temporal and spatial contexts (ie …

The brain is the key organ of stress reactivity, coping, and recovery processes. Within the
brain, a distributed neural circuitry determines what is threatening and thus stressful to the …

The brain is the key organ of stress processes. It determines what individuals will experience
as stressful, it orchestrates how individuals will cope with stressful experiences, and it …

Highlights•Stress and depression are characterized by loss of synapses in prefrontal
cortex.•Rapid acting antidepressants increase synaptic contacts in prefrontal cortex.•NMDA …

The last decade has seen a burgeoning of reports associating brain structure with specific
skills and traits (eg,[1–8]). Although these cross-sectional studies are informative, cause and …

Late adulthood is associated with increased hippocampal atrophy and dysfunction. Although
there are multiple paths by which hippocampal deterioration occurs in late life, the authors …