Abstract gamma-Aminobutyric acid (GABA)-mediated inhibitory neurotransmission and the
gene products involved were discovered during the mid-twentieth century. Historically …

GABAA receptors are the major inhibitory transmitter receptors in the brain. They are ligand-
gated chloride channels and the site of action of benzodiazepines, barbiturates, neuroactive …

In this review we attempt to summarize experimental evidence on the existence of defined
native GABAA receptor subtypes and to produce a list of receptors that actually seem to exist …

The fundamental principle that unites addictive drugs appears to be that each enhances
synaptic dopamine by means that dissociate it from normal behavioral control, so that they …

Neuroactive steroids are natural or synthetic steroids that rapidly alter the excitability of
neurons by binding to membrane‐bound receptors such as those for inhibitory and (or) …

GABAA‐receptors display an extensive structural heterogeneity based on the differential
assembly of a family of at least 15 subunits (α1–6, β1–3, γ1–3, θ, ρl–2) into distinct …

Introduction The steroid hormones constitute a very important class of compounds and are
present in most species. The hormones that are synthesized in the adrenal gland, namely …

It inhibits neuronal firing by increasing a Cl-conductance. Bicuculline blocks this effect and
induces interictal discharges. A different picture is present in neonatal hippocampal …

GABA A receptors are a heterogeneous family of ligand-gated ion channels responsible for
mediating inhibitory neurotransmission in the CNS. Since the identification of mammalian …

The concept of moderate consumption of ethanol (beverage alcohol) has evolved over time
from considering this level of intake to be nonintoxicating and noninjurious, to …