Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …

Pseudomonas aeruginosa is an opportunistic pathogen that is a leading cause of morbidity
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …

To support an ever-increasing population, modern agriculture faces numerous challenges
that pose major threats to global food and energy security. Plant-associated microbes, with …

Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

Antibiotics target energy-consuming processes. As such, perturbations to bacterial metabolic
homeostasis are significant consequences of treatment. Here, we describe three postulates …

With the emerging threat of infections caused by multidrug resistant bacteria, phages have
been reconsidered as an alternative for treating infections caused by tenacious pathogens …

The rapid emergence of antibiotic-resistant infections is prompting increased interest in
phage-based antimicrobials. However, acquisition of resistance by bacteria is a major issue …

Viruses that infect bacteria (bacteriophages; also known as phages) were discovered 100
years ago. Since then, phage research has transformed fundamental and translational …

Bacteriophage particles are the most abundant biological entities on our planet, infecting
specific bacterial hosts in every known environment and being major drivers of bacterial …

Bacteria can be genetically engineered to kill specific pathogens or inhibit their virulence.
We previously developed a synthetic genetic system that allows a laboratory strain of …