Immunoinformatics and vaccine development: an overview

AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020 - Taylor & Francis
The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …

Vaccine prevention of meningococcal disease in Africa: Major advances, remaining challenges

MM Mustapha, LH Harrison - Human Vaccines & …, 2018 - Taylor & Francis
Africa historically has had the highest incidence of meningococcal disease with high
endemic rates and periodic epidemics. The meningitis belt, a region of sub-Saharan Africa …

Whole Genome Analyses Accurately Identify Neisseria spp. and Limit Taxonomic Ambiguity

M Khoder, M Osman, II Kassem, R Rafei… - International Journal of …, 2022 - mdpi.com
Genome sequencing facilitates the study of bacterial taxonomy and allows the re-evaluation
of the taxonomic relationships between species. Here, we aimed to analyze the draft …

Microevolution of Neisseria lactamica during nasopharyngeal colonisation induced by controlled human infection

A Pandey, DW Cleary, JR Laver, A Gorringe… - Nature …, 2018 - nature.com
Neisseria lactamica is a harmless coloniser of the infant respiratory tract, and has a mutually-
excluding relationship with the pathogen Neisseria meningitidis. Here we report controlled …

Pangenome graphs in infectious disease: a comprehensive genetic variation analysis of Neisseria meningitidis leveraging Oxford Nanopore long reads

Z Yang, A Guarracino, PJ Biggs, MA Black… - Frontiers in …, 2023 - frontiersin.org
Whole genome sequencing has revolutionized infectious disease surveillance for tracking
and monitoring the spread and evolution of pathogens. However, using a linear reference …

Virulence genes and previously unexplored gene clusters in four commensal Neisseria spp. isolated from the human throat expand the neisserial gene repertoire

A Calder, CJ Menkiti, A Çağdaş… - Microbial …, 2020 - microbiologyresearch.org
Commensal non-pathogenic Neisseria spp. live within the human host alongside the
pathogenic Neisseria meningitidis and Neisseria gonorrhoeae and due to natural …

[HTML][HTML] The global meningitis genome partnership

E Rodgers, SD Bentley, R Borrow, HB Bratcher… - Journal of Infection, 2020 - Elsevier
Genomic surveillance of bacterial meningitis pathogens is essential for effective disease
control globally, enabling identification of emerging and expanding strains and consequent …

The CRISPR/Cas system in Neisseria meningitidis affects bacterial adhesion to human nasopharyngeal epithelial cells

N Heidrich, A Hagmann, S Bauriedl, J Vogel… - RNA biology, 2019 - Taylor & Francis
Neisseria meningitidis, a commensal β-proteobacterium of the human nasopharynx,
constitutes a worldwide leading cause of sepsis and epidemic meningitis. A recent genome …

Use of Andromas and Bruker MALDI-TOF MS in the identification of Neisseria

F Morel, H Jacquier, M Desroches, V Fihman… - European Journal of …, 2018 - Springer
Through the past decade, MALDI-TOF MS has been recognized as a fast and robust tool for
identification of most bacteria in clinical microbiology. However, the accuracy of this method …

[HTML][HTML] Genetic diversity of Neisseria gonorrhoeae multi-antigen sequence types in Russia and Europe

B Shaskolskiy, E Dementieva, I Kandinov… - International Journal of …, 2020 - Elsevier
Objectives The goal of this work was to assess the genetic diversity of Neisseria
gonorrhoeae isolates in Russia and Europe and to compare the distribution of the N …