Toxicity of nanoparticles in biomedical application: nanotoxicology
Nanoparticles are of great importance in development and research because of their
application in industries and biomedicine. The development of nanoparticles requires …
application in industries and biomedicine. The development of nanoparticles requires …
[HTML][HTML] Challenges and opportunities to penetrate the blood-brain barrier for brain cancer therapy
DH Upton, C Ung, SM George, M Tsoli, M Kavallaris… - Theranostics, 2022 - ncbi.nlm.nih.gov
Despite significant advances in research, the prognosis for both primary and secondary
brain cancers remains poor. The blood-brain barrier (BBB) is a complex and unique semi …
brain cancers remains poor. The blood-brain barrier (BBB) is a complex and unique semi …
Getting into the brain: liposome-based strategies for effective drug delivery across the blood–brain barrier
DB Vieira, LF Gamarra - International journal of nanomedicine, 2016 - Taylor & Francis
This review summarizes articles that have been reported in literature on liposome-based
strategies for effective drug delivery across the blood–brain barrier. Due to their unique …
strategies for effective drug delivery across the blood–brain barrier. Due to their unique …
Overcoming the blood–brain tumor barrier for effective glioblastoma treatment
O Van Tellingen, B Yetkin-Arik, MC De Gooijer… - Drug Resistance …, 2015 - Elsevier
Gliomas are the most common primary brain tumors. Particularly in adult patients, the vast
majority of gliomas belongs to the heterogeneous group of diffuse gliomas, ie. glial tumors …
majority of gliomas belongs to the heterogeneous group of diffuse gliomas, ie. glial tumors …
Neurotoxicity of nanomaterials: An up-to-date overview
The field of nanotechnology, through which nanomaterials are designed, characterized,
produced, and applied, is rapidly emerging in various fields, including energy, electronics …
produced, and applied, is rapidly emerging in various fields, including energy, electronics …
Nanogels as novel nanocarrier systems for efficient delivery of CNS therapeutics
Y Zhang, Z Zou, S Liu, S Miao, H Liu - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Nanogels have come out as a great potential drug delivery platform due to its prominently
high colloidal stability, high drug loading, core-shell structure, good permeation property and …
high colloidal stability, high drug loading, core-shell structure, good permeation property and …
Extracellular vesicles for the treatment of central nervous system diseases
V Gratpain, A Mwema, Y Labrak, GG Muccioli… - Advanced drug delivery …, 2021 - Elsevier
The interest in extracellular vesicles (EVs) increased during the last decade. It is now
established that these vesicles play a role in the pathogenesis of central nervous system …
established that these vesicles play a role in the pathogenesis of central nervous system …
Nanoparticles: A Hope for the Treatment of Inflammation in CNS
FD Zhu, YJ Hu, L Yu, XG Zhou, JM Wu… - Frontiers in …, 2021 - frontiersin.org
Neuroinflammation, an inflammatory response within the central nervous system (CNS), is a
main hallmark of common neurodegenerative diseases, including Alzheimer's disease (AD) …
main hallmark of common neurodegenerative diseases, including Alzheimer's disease (AD) …
Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures malignant glioma in rats
C Zhang, EA Nance, P Mastorakos, J Chisholm… - Journal of Controlled …, 2017 - Elsevier
Glioblastoma multiforme (GBM) is highly invasive and uniformly fatal, with median survival<
20 months after diagnosis even with the most aggressive treatment that includes surgery …
20 months after diagnosis even with the most aggressive treatment that includes surgery …
MR image-guided delivery of cisplatin-loaded brain-penetrating nanoparticles to invasive glioma with focused ultrasound
Systemically administered chemotherapeutic drugs are often ineffective in the treatment of
invasive brain tumors due to poor therapeutic index. Within gliomas, despite the presence of …
invasive brain tumors due to poor therapeutic index. Within gliomas, despite the presence of …