An overview of proceedings, findings, and recommendations from the workshop on
“Advancing Symptom Science Through Symptom Cluster Research” sponsored by the …

This paper describes the effects of immune genes genetic variants and mRNA expression
on depression's risk, severity, and response to antidepressant treatment, through a …

Purpose Breast cancer survivors may experience pain, fatigue, or psychological distress as
a result of the treatment. These symptoms may co-occur and form a cluster. However little is …

Severe fatigue occurs in one in four breast cancer survivors (BCS). Quality of life (QOL) and
psychological factors are important in fatigue-oriented interventions for BCS, but an up-to …

Purpose Sleep disturbance and cancer-related fatigue (CRF) are among the most commonly
reported symptoms associated with breast cancer and its treatment. This study identified …

Objectives To discuss the importance of cancer symptom clusters in clinical practice, review
evidence for symptom cluster interventions, and make recommendations for symptom cluster …

Context Symptom researchers have proposed a model of inflammatory cytokine activity and
dysregulation in cancer to explain co-occurring symptoms including pain, fatigue, and sleep …

Chemotherapy-induced peripheral neuropathy (CIPN) is a side effect of chemotherapics
such as taxanes, vinca alkaloids, and platinum compounds. In recent years, several reports …

Context The existence of stable symptom clusters with variations or changes in cluster
membership and the merging of symptom clusters over time urge us to investigate how …

Context Pain, fatigue, sleep disturbance, and depression often co-occur in oncology patients
and negatively impact quality of life (QOL). Objectives Study purposes were to identify …