Mannosylation in Candida albicans: role in cell wall function and immune recognition

RA Hall, NAR Gow - Molecular microbiology, 2013 - Wiley Online Library
The fungal cell wall is a dynamic organelle required for cell shape, protection against the
environment and, in pathogenic species, recognition by the innate immune system. The …

Candida albicans Virulence Factors and Pathogenicity for Endodontic Infections

YJ Yoo, AR Kim, H Perinpanayagam, SH Han, KY Kum - Microorganisms, 2020 - mdpi.com
Candida albicans (C. albicans) is the fungus most frequently isolated from endodontic root
canal infections. Although recognized by dental pulp and periradicular tissue cells that elicit …

Innate immune responses against the fungal pathogen Candida auris

Y Wang, Y Zou, X Chen, H Li, Z Yin, B Zhang… - Nature …, 2022 - nature.com
Candida auris is a multidrug-resistant human fungal pathogen responsible for nosocomial
outbreaks worldwide. Although considerable progress has increased our understanding of …

Pathogenesis of dermatophytosis: sensing the host tissue

NM Martinez-Rossi, NTA Peres, A Rossi - Mycopathologia, 2017 - Springer
Abstract The genera Trichophyton, Microsporum, and Epidermophyton include filamentous
fungi that cause dermatophytosis, a superficial infection of the skin, stratum corneum, nail …

Sublethal sperm freezing damage: Manifestations and solutions

T Pini, T Leahy, SP de Graaf - Theriogenology, 2018 - Elsevier
Semen cryopreservation is an important tool for artificial breeding, species conservation and
human reproductive medicine. However, sublethal freezing damage remains an important …

Stage Specific Assessment of Candida albicans Phagocytosis by Macrophages Identifies Cell Wall Composition and Morphogenesis as Key Determinants

LE Lewis, JM Bain, C Lowes, C Gillespie… - PLoS …, 2012 - journals.plos.org
Candida albicans is a major life-threatening human fungal pathogen. Host defence against
systemic Candida infection relies mainly on phagocytosis of fungal cells by cells of the …

Deletion of the α-(1,3)-Glucan Synthase Genes Induces a Restructuring of the Conidial Cell Wall Responsible for the Avirulence of Aspergillus fumigatus

A Beauvais, S Bozza, O Kniemeyer, C Formosa… - PLoS …, 2013 - journals.plos.org
α-(1, 3)-Glucan is a major component of the cell wall of Aspergillus fumigatus, an
opportunistic human fungal pathogen. There are three genes (AGS1, AGS2 and AGS3) …

The Mnn2 Mannosyltransferase Family Modulates Mannoprotein Fibril Length, Immune Recognition and Virulence of Candida albicans

RA Hall, S Bates, MD Lenardon, DM MacCallum… - PLoS …, 2013 - journals.plos.org
The fungal cell wall is the first point of interaction between an invading fungal pathogen and
the host immune system. The outer layer of the cell wall is comprised of GPI anchored …

Thriving within the host: Candida spp. interactions with phagocytic cells

P Miramón, L Kasper, B Hube - Medical microbiology and immunology, 2013 - Springer
Certain Candida spp.(eg C. albicans, C. tropicalis, C. parapsilosis and C. glabrata) are not
only well-adapted fungal commensals of humans, but are also able to cause superficial …

Candida auris cell wall mannosylation contributes to neutrophil evasion through pathways divergent from Candida albicans and Candida glabrata

MV Horton, CJ Johnson, R Zarnowski, BD Andes… - MSphere, 2021 - Am Soc Microbiol
Candida auris, a recently emergent fungal pathogen, has caused invasive infections in
health care settings worldwide. Mortality rates approach 60% and hospital spread poses a …