Causes and consequences of snake venom variation
Snake venoms are mixtures of toxins that vary extensively between and within snake
species. This variability has serious consequences for the management of the world's 1.8 …
species. This variability has serious consequences for the management of the world's 1.8 …
Scorpion venom: detriments and benefits
Scorpion venom may cause severe medical complications and untimely death if injected into
the human body. Neurotoxins are the main components of scorpion venom that are known to …
the human body. Neurotoxins are the main components of scorpion venom that are known to …
The Indian cobra reference genome and transcriptome enables comprehensive identification of venom toxins
K Suryamohan, SP Krishnankutty, J Guillory, M Jevit… - Nature Genetics, 2020 - nature.com
Snakebite envenoming is a serious and neglected tropical disease that kills~ 100,000
people annually. High-quality, genome-enabled comprehensive characterization of toxin …
people annually. High-quality, genome-enabled comprehensive characterization of toxin …
History of envenoming therapy and current perspectives
MB Pucca, FA Cerni, R Janke… - Frontiers in …, 2019 - frontiersin.org
Each year, millions of humans fall victim to animal envenomings, which may either be
deadly or cause permanent disability to the effected individuals. The Nobel Prize-winning …
deadly or cause permanent disability to the effected individuals. The Nobel Prize-winning …
The urgent need to develop novel strategies for the diagnosis and treatment of snakebites
HF Williams, HJ Layfield, T Vallance, K Patel… - Toxins, 2019 - mdpi.com
Snakebite envenoming (SBE) is a priority neglected tropical disease, which kills in excess of
100,000 people per year. Additionally, many millions of survivors also suffer through …
100,000 people per year. Additionally, many millions of survivors also suffer through …
The search for natural and synthetic inhibitors that would complement antivenoms as therapeutics for snakebite envenoming
A global strategy, under the coordination of the World Health Organization, is being unfolded
to reduce the impact of snakebite envenoming. One of the pillars of this strategy is to ensure …
to reduce the impact of snakebite envenoming. One of the pillars of this strategy is to ensure …
Old World Vipers—a review about snake venom proteomics of Viperinae and their variations
Fine-tuned by millions of years of evolution, snake venoms have frightened but also
fascinated humanity and nowadays they constitute potential resources for drug …
fascinated humanity and nowadays they constitute potential resources for drug …
Snake three-finger α-neurotoxins and nicotinic acetylcholine receptors: Molecules, mechanisms and medicine
S Nirthanan - Biochemical pharmacology, 2020 - Elsevier
Snake venom three-finger α-neurotoxins (α-3FNTx) act on postsynaptic nicotinic
acetylcholine receptors (nAChRs) at the neuromuscular junction (NMJ) to produce skeletal …
acetylcholine receptors (nAChRs) at the neuromuscular junction (NMJ) to produce skeletal …
[HTML][HTML] Clinical management of snakebite envenoming: future perspectives
Snakebite envenoming is a major cause of morbidity and mortality in rural communities
throughout the tropics. Generally, the main clinical features of snakebites are local swelling …
throughout the tropics. Generally, the main clinical features of snakebites are local swelling …
[HTML][HTML] Strategies for heterologous expression, synthesis, and purification of animal venom toxins
E Rivera-de-Torre, C Rimbault, TP Jenkins… - … in bioengineering and …, 2022 - frontiersin.org
Animal venoms are complex mixtures containing peptides and proteins known as toxins,
which are responsible for the deleterious effect of envenomations. Across the animal …
which are responsible for the deleterious effect of envenomations. Across the animal …