Metalloenzymes catalyze a variety of reactions using a limited number of natural amino
acids and metallocofactors. Therefore, the environment beyond the primary coordination …

The 5-10-methylenetetrahydrofolate reductase (MTHFR) enzyme is vital for cellular
homeostasis due to its key functions in the one-carbon cycle, which include methionine and …

Abstract oxidative stress is caused by an abundant generation of reactive oxygen species,
associated to a diminished capacity of the endogenous systems of the organism to …

BACKGROUND Nearly every plant, animal, and environment on earth is host to a diverse
community of microorganisms that influence each other and their environment …

Organic acidemias such as methylmalonic acidemia (MMA) are a group of inborn errors of
metabolism that typically arise from defects in the catabolism of amino and fatty acids …

Many microbial producers of coenzyme B12 family cofactors together with their metabolically
interdependent pathways are comprehensively studied and successfully used both in …

The serine-glycine-one-carbon (SGOC) metabolic pathway is critical for DNA methylation,
histone methylation, and redox homeostasis, in addition to protein, lipid, and nucleotide …

Graphene based nanomaterials are explored in the field of cancer bioimaging and
biomedical science and engineering. The luminescent nanostructures with a low toxicity and …

As one of the bicyclic metabolic pathways of one-carbon metabolism, methionine
metabolism is the pivot linking the folate cycle to the transsulfuration pathway. In addition to …

Cerebral ischemia-reperfusion injury (CIRI) is often accompanied by upregulation of
homocysteine (Hcy). Excessive Hcy damages cerebral vascular endothelial cells and …