The development of late-stage functionalization (LSF) methodologies, particularly C–H
functionalization, has revolutionized the field of organic synthesis. Over the past decade …

Radical aryl migrations are powerful techniques to forge new bonds in aromatic compounds.
The growing popularity of photoredox catalysis has led to an influx of novel strategies to …

We report herein a modular class of organic catalysts that, acting as donors, can readily form
photoactive electron donor–acceptor (EDA) complexes with a variety of radical precursors …

Reactions that involve the addition of carbon‐centered radicals to basic heteroarenes,
followed by formal hydrogen atom loss, have become widely known as Minisci‐type …

Photomediated Giese reactions are at the forefront of radical chemistry, much like the
classical tin‐mediated Giese reactions were nearly forty years ago. With the global …

The selective and efficient C–H methylation of sp2 and sp3 carbon centres has become a
powerful transformation in the synthetic toolbox. Due to the potential for profound changes to …

Basic heteroarenes are a ubiquitous feature of pharmaceuticals and bioactive molecules,
and Minisci-type additions of radical nucleophiles are a leading method for their elaboration …

The direct functionalization of C H bonds in organic compounds has recently emerged as a
powerful and ideal method for the formation of carbon–carbon and carbon–heteroatom …

A chiral phosphine oxide-ligated Ni–Al bimetallic catalyst was used to realize an
enantioselective C2–H alkylation of pyridines without the need of a C2-block. A wide range …

Introduction: Late-stage functionalization (LSF) can introduce important chemical groups in
the very last steps of the synthesis. LSF has the potential to speed up the preparation of …