Objective: The aim of this meta-analysis was to summarize the current available evidence on
nonoperative management (NOM) with antibiotics for uncomplicated appendicitis, both in …

Appendicitis is a common occurrence in both the adult and pediatric populations. The
condition most commonly occurs between the ages of 10 and 20 years with a lifetime risk of …

Background Antibiotic therapy has been proposed as an alternative to surgery for the
treatment of appendicitis. Methods We conducted a pragmatic, nonblinded, noninferiority …

Importance Short-term results support antibiotics as an alternative to surgery for treating
uncomplicated acute appendicitis, but long-term outcomes are not known. Objective To …

Background Surgical strategies are being adapted to face the COVID‐19 pandemic.
Recommendations on the management of acute appendicitis have been based on expert …

Key Clinical Points Treatment of Acute Uncomplicated Appendicitis Patients with acute,
localized, uncomplicated appendicitis (approximately 80% of all appendicitis cases) are …

Importance Antibiotics are an effective and safe alternative to appendectomy for managing
uncomplicated acute appendicitis, but the optimal antibiotic regimen is not known. Objective …

Purpose To perform a systematic review and meta-analysis to identify computed
tomographic (CT) features for differentiating complicated appendicitis in patients suspected …

Background This aim of this study was to provide an updated meta-analysis comparing
antibiotic therapy with appendicectomy in adults (16 years or older) with uncomplicated …

Importance Use of antibiotics for the treatment of appendicitis is safe and has been found to
be noninferior to appendectomy based on self-reported health status at 30 days. Identifying …