[HTML][HTML] EMT mechanism in breast cancer metastasis and drug resistance: Revisiting molecular interactions and biological functions

M Hashemi, HZ Arani, S Orouei, S Fallah… - Biomedicine & …, 2022 - Elsevier
One of the malignant tumors in women that has involved both developed and developing
countries is breast cancer. Similar to other types of tumors, breast cancer cells demonstrate …

The roles of m6A methylation in cervical cancer: functions, molecular mechanisms, and clinical applications

Z Mao, B Wang, T Zhang, B Cui - Cell Death & Disease, 2023 - nature.com
Cervical cancer (CC) is a gynecological neoplasm with the highest incidence rate, primarily
attributed to the persistent infection of high-risk Human papillomavirus (HPV). Despite …

Osteopontin in cancer: mechanisms and therapeutic targets

Y Kariya, Y Kariya - International Journal of Translational Medicine, 2022 - mdpi.com
Despite significant advances in the understanding of cancer biology, cancer is still a leading
cause of death worldwide. Expression of the tumor microenvironment component …

TTN mutations predict a poor prognosis in patients with thyroid cancer

X Han, J Chen, J Wang, J Xu, Y Liu - Bioscience Reports, 2022 - portlandpress.com
Objective: We aimed to investigate the relationship between titin (TTN) gene mutations and
thyroid cancer (THCA) and to explore the feasibility of the TTN gene as a potential …

Aberrant expression of bone morphogenetic proteins in the disease progression and metastasis of breast cancer

M Liu, L Sui, Z Fang, WG Jiang, L Ye - Frontiers in Oncology, 2023 - frontiersin.org
Background Bone morphogenetic proteins (BMPs) play crucial roles in the tumorigenesis
and metastasis of cancers. Controversy remains about the exact implications of BMPs and …

Comparative N-Glycoproteomic Investigation of Eggshell Cuticle and Mineralized Layer Proteins

L Zeng, X Shi, L Xuan, J Zheng - Journal of Agricultural and Food …, 2023 - ACS Publications
The eggshell cuticle layer (ECL) and eggshell mineralized layer (EML) contain amounts of
glycoproteins and proteoglycans. However, there were few comprehensive reports about the …

Fam20c regulates the calpain proteolysis system through phosphorylating Calpasatatin to maintain cell homeostasis

X Liu, L Jiang, W Zhang, J Zhang, X Luan… - Journal of Translational …, 2023 - Springer
Background The family with sequence similarity 20-member C (FAM20C) kinase, a Golgi
casein kinase, which is responsible for phosphorylating the majority of the extracellular …

Animal models of cancer metastasis to the bone

Y Yu, K Li, Y Peng, W Wu, F Chen, Z Shao… - Frontiers in …, 2023 - frontiersin.org
Cancer metastasis is a major cause of mortality from several tumors, including those of the
breast, prostate, and the thyroid gland. Since bone tissue is one of the most common sites of …

Passing the post: roles of posttranslational modifications in the form and function of extracellular matrix

JC Adams - American Journal of Physiology-Cell …, 2023 - journals.physiology.org
The extracellular matrix (ECM) is central to the physiology of animal tissues, through its
multifaceted roles in tissue structure, mechanical properties, and cell interactions, and by its …

Is osteopontin a good marker for bone metastasis in canine mammary gland tumor and prostate cancer?

C Grisoni Sanchez, ML Figueiredo… - Animals, 2023 - mdpi.com
Simple Summary Bone metastasis can develop from several tumor subtypes, and the
presence of bone metastasis confers a negative prognosis to patients. In dogs, a small …