Myocardial infarction and subsequent heart failure is a major health burden associated with
significant mortality and morbidity in western societies. The ability of cardiac tissue to …

Angiogenesis is a common feature of many physiological processes and pathological
conditions. RGD-containing peptides can strongly bind to integrin αvβ3 expressed on …

Using endogenous mesenchymal stem cells for treating myocardial infarction and other
cardiovascular conditions typically results in poor efficacy, in part owing to the heterogeneity …

The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
that causes coronavirus disease 2019 (COVID-19) has led to 47 m infected cases and 1. 2 m …

Purpose Increased angiogenesis after myocardial infarction is considered an important
favorable prognostic parameter. The αvβ3 integrin is a key mediator of cell-cell and cell …

Cardiovascular diseases (CVD) is a collective term describing a range of conditions that
affect the heart and blood vessels. Due to the varied nature of the disorders, distinguishing …

Mesenchymal stem cells (MSCs) are an appealing potential therapy for vascular diseases;
however, many challenges remain in their clinical translation. While the use of biochemical …

Background Radiolabeled RGD peptides detect α v β 3 integrin expression associated with
angiogenesis and extracellular matrix remodeling after myocardial infarction. We studied …

Abstract Purpose of Review Myocardial infarction (MI) leading to heart failure displays an
important cause of death worldwide. Adequate restoration of blood flow to prevent this …

Angiogenesis is considered integral to the reparative process after ischemic injury. The αvβ3
integrin is a critical modulator of angiogenesis and highly expressed in activated endothelial …