Frontocingulate dysfunction in depression: toward biomarkers of treatment response

DA Pizzagalli - Neuropsychopharmacology, 2011 - nature.com
Increased rostral anterior cingulate cortex (rACC) activity has emerged as a promising
predictor of treatment response in depression, but neither the reliability of this relationship …

[HTML][HTML] Diffusion tensor imaging of the brain

AL Alexander, JE Lee, M Lazar, AS Field - Neurotherapeutics, 2007 - Elsevier
Diffusion tensor imaging (DTI) is a promising method for characterizing microstructural
changes or differences with neuropathology and treatment. The diffusion tensor may be …

Depression in the elderly

GS Alexopoulos - The lancet, 2005 - thelancet.com
In elderly people, depression mainly affects those with chronic medical illnesses and
cognitive impairment, causes suffering, family disruption, and disability, worsens the …

[HTML][HTML] Diffusion tensor imaging of cerebral white matter integrity in cognitive aging

DJ Madden, IJ Bennett, A Burzynska, GG Potter… - … et Biophysica Acta (BBA …, 2012 - Elsevier
In this article we review recent research on diffusion tensor imaging (DTI) of white matter
(WM) integrity and the implications for age-related differences in cognition. Neurobiological …

Is depression a disconnection syndrome? Meta-analysis of diffusion tensor imaging studies in patients with MDD

Y Liao, X Huang, Q Wu, C Yang, W Kuang, M Du… - Journal of Psychiatry and …, 2013 - jpn.ca
Background: Many studies using diffusion tensor imaging (DTI) have demonstrated impaired
white matter integrity in patients with major depressive disorder (MDD), with significant …

Functional connectivity in the cognitive control network and the default mode network in late-life depression

GS Alexopoulos, MJ Hoptman, D Kanellopoulos… - Journal of affective …, 2012 - Elsevier
BACKGROUND: Abnormalities have been identified in the Cognitive Control Network (CCN)
and the Default Mode Network (DMN) during episodes of late-life depression. This study …

Electroconvulsive therapy for depression

SH Lisanby - New England Journal of Medicine, 2007 - Mass Medical Soc
An 82-year-old woman with severe depression, including psychotic symptoms, is referred for
consideration of electroconvulsive therapy. She has had four episodes of major depression …

Neuroimaging studies of mood disorder effects on the brain

YI Sheline - Biological psychiatry, 2003 - Elsevier
Studies of early-onset recurrent depression, late life depression associated with neurologic
disorders, and bipolar illness have revealed structural brain changes within a …

Predictive neural biomarkers of clinical response in depression: a meta-analysis of functional and structural neuroimaging studies of pharmacological and …

CHY Fu, H Steiner, SG Costafreda - Neurobiology of disease, 2013 - Elsevier
We performed a systematic review and meta-analysis of neural predictors of response to the
most commonly used, evidence based treatments in clinical practice, namely …

The neurobiology of depression in later-life: clinical, neuropsychological, neuroimaging and pathophysiological features

SL Naismith, LM Norrie, L Mowszowski… - Progress in neurobiology, 2012 - Elsevier
As the population ages, the economic and societal impacts of neurodegenerative and
neuropsychiatric disorders are expected to rise sharply. Like dementia, late-life depressive …