Resistance-proof antimicrobial drug discovery to combat global antimicrobial resistance threat

A Upadhayay, J Ling, D Pal, Y Xie, FF Ping… - Drug Resistance …, 2023 - Elsevier
Drug resistance is well-defined as a serious problem in our living world. To survive,
microbes develop defense strategies against antimicrobial drugs. Drugs exhibit less or no …

A spotlight on the diagnostic methods of a fatal disease Visceral Leishmaniasis

A Kumar, SC Pandey, M Samant - Parasite Immunology, 2020 - Wiley Online Library
Leishmania donovani (a causative agent of visceral leishmaniasis) poses a serious health
threat to the human population which is fatal if left untreated. The life cycle of Leishmania …

[HTML][HTML] Antiprotozoal Activity of Turkish Origanum onites Essential Oil and Its Components

D Tasdemir, M Kaiser, B Demirci, F Demirci… - Molecules, 2019 - mdpi.com
Essential oil of Origanum species is well known for antimicrobial activity, but only a few have
been evaluated in narrow spectrum antiprotozoal assays. Herein, we assessed the …

Genetically modified live attenuated vaccine: A potential strategy to combat visceral leishmaniasis

SC Pandey, A Kumar, M Samant - Parasite Immunology, 2020 - Wiley Online Library
Visceral leishmaniasis (VL) is caused by a protozoan parasite Leishmania donovani mainly
influencing the population of tropical and subtropical regions across the globe. The arsenal …

Molecular docking and molecular dynamics simulation approaches for evaluation of laccase-mediated biodegradation of various industrial dyes

V Pande, T Joshi, SC Pandey, D Sati… - Journal of …, 2022 - Taylor & Francis
Dyes are being increasingly utilized across the globe, but there is no appropriate method of
bioremediation for their full mineralization from the environment. Laccases are key enzymes …

Happy birthday: 30 years of RNA helicases

M Valentini, P Linder - RNA Remodeling Proteins: Methods and Protocols, 2021 - Springer
RNA helicases are ubiquitous, highly conserved RNA-binding enzymes that use the energy
derived from the hydrolysis of nucleoside triphosphate to modify the structure of RNA …

DNA-based microarray studies in visceral leishmaniasis: identification of biomarkers for diagnostic, prognostic and drug target for treatment

A Kumar, SC Pandey, M Samant - Acta tropica, 2020 - Elsevier
Visceral leishmaniasis (VL) is one of the major infectious diseases affecting the poorest
regions of the world. Current therapy is not very much satisfactory. The alarming rise of drug …

[HTML][HTML] DDX3 DEAD-box RNA helicase (Hel67) gene disruption impairs infectivity of Leishmania donovani and induces protective immunity against visceral …

SC Pandey, V Pande, M Samant - Scientific reports, 2020 - nature.com
Visceral leishmaniasis (VL) is a vector-borne disease caused by the digenetic protozoan
parasite Leishmania donovani complex. So far there is no effective vaccine available …

[HTML][HTML] Anti-protozoal activity of Thymol and a Thymol ester against Cryptosporidium parvum in cell culture

A Dominguez-Uscanga, DF Aycart, K Li… - International Journal for …, 2021 - Elsevier
Cryptosporidium parvum is a protozoan parasite that infects intestinal epithelial cells
causing malabsorption and severe diarrhea. The monoterpene thymol has been reported to …

Identification of trans-2-cis-8-Matricaria-ester from the Essential Oil of Erigeron multiradiatus and Evaluation of Its Antileishmanial Potential by in Vitro and in Silico …

S Chandra Pandey, DS Dhami, A Jha… - ACS …, 2019 - ACS Publications
The essential oil (EO) composition of the aerial parts of Erigeron multiradiatus (Lindl. ex DC.)
Benth growing wild in the central Himalayan region of Uttarakhand, India, was analyzed by …