ANGPTL8 in metabolic homeostasis: more friend than foe?

C Guo, C Wang, X Deng, J He, L Yang… - Open …, 2021 - royalsocietypublishing.org
ANGPTL8 is an important cytokine, which is significantly increased in type 2 diabetes
mellitus (T2DM), obesity and metabolic syndrome. Many studies have shown that ANGPTL8 …

[HTML][HTML] Omics-based biomarkers in the diagnosis of diabetes

WZ Gan, V Ramachandran, CSY Lim… - Journal of Basic and …, 2020 - degruyter.com
Diabetes mellitus (DM) is a group of metabolic diseases related to the dysfunction of insulin,
causing hyperglycaemia and life-threatening complications. Current early screening and …

[HTML][HTML] Circulating angiopoietin-like protein 8 (betatrophin) association with HsCRP and metabolic syndrome

M Abu-Farha, J Abubaker, I Al-Khairi, P Cherian… - Cardiovascular …, 2016 - Springer
Background ANGPTL8 also called betatrophin is a regulator of lipid metabolism through its
interaction with ANGPTL3. It has also been suggested to play a role in insulin resistance and …

[HTML][HTML] Association between usual alcohol consumption and risk of falls in middle-aged and older Chinese adults

Y Sun, B Zhang, Q Yao, Y Ma, Y Lin, M Xu, M Hu, J Hao… - BMC geriatrics, 2022 - Springer
Background Previous studies exploring usual alcohol consumption and falls risk were
scarce in China. In addition, the dose–response relationship has not been explored so far …

Altered concentrations in dyslipidemia evidence a role for ANGPTL8/betatrophin in lipid metabolism in humans

J Gómez-Ambrosi, E Pascual-Corrales… - The Journal of …, 2016 - academic.oup.com
Context: Angiopoietin-like protein 8 (ANGPTL8)/betatrophin is a secreted protein initially
involved in β-cell replication. Recent data in humans and mice models suggest that …

[HTML][HTML] Interaction between endothelial nitric oxide synthase rs1799983, cholesteryl ester-transfer protein rs708272 and angiopoietin-like protein 8 rs2278426 gene …

D El-Lebedy - Cardiovascular diabetology, 2018 - Springer
Background The aim of the present study was to examine the association of angiopoietin-
like proteins-8 (ANGPTL8) rs2278426, cholesteryl ester-transfer protein (CETP) rs708272 …

[HTML][HTML] Vitamin D modifies the associations between circulating betatrophin and cardiometabolic risk factors among youths at risk for metabolic syndrome

J Fu, C Hou, L Li, D Feng, G Li, M Li, C Li… - Cardiovascular …, 2016 - Springer
Background Betatrophin has been recently reported to play a role in glucose homeostasis
by inducing beta-cell proliferation in mice. However, studies in human are inconsistent. As a …

Circulating betatrophin concentration is negatively correlated with insulin resistance in obese children and adolescents

H Tuhan, A Abacı, A Anık, G Çatlı, T Küme… - Diabetes research and …, 2016 - Elsevier
Aim The current study aimed to investigate the relationship between serum betatrophin
levels and metabolic and anthropometric parameters in obese children. Method The study …

[HTML][HTML] Circulating angiopoietin-like protein 8 (ANGPTL8) and ANGPTL3 concentrations in relation to anthropometric and metabolic profiles in Korean children: a …

HS Chung, MJ Lee, SY Hwang, HJ Lee, HJ Yoo… - Cardiovascular …, 2016 - Springer
Background Previous studies have shown that angiopoietin-like protein 8 (ANGPTL8), also
called as betatrophin, acts together with ANGPTL3 to regulate lipid metabolism, glucose …

High betatrophin in coronary patients protects from cardiovascular events

A Leiherer, J Ebner, A Muendlein, EM Brandtner… - Atherosclerosis, 2020 - Elsevier
Background and aims Betatrophin, also known as angiopoietin-like protein 8 (ANGPTL8) or
lipasin, is a nutritionally-regulated mammalian-specific protein secreted by the liver and …