The current unidimensional paradigm of kidney disease detection is incompatible with the
complexity and heterogeneity of renal pathology. The diagnosis of kidney disease has …

IgA nephropathy (IgAN) is the most common primary glomerulonephritis, frequently leading
to end-stage renal disease, as there is no disease-specific therapy. IgAN is diagnosed from …

Chronic kidney disease (CKD) affects 8 to 16% people worldwide, with an increasing
incidence and prevalence of end-stage kidney disease (ESKD). The effective management …

Chronic kidney disease (CKD) is a major health and economic burden with a rising
incidence. During progression of CKD, the sustained release of proinflammatory and …

The difficulties in defining the natural history of primary IgA nephropathy (IgAN) depend
upon the pre-selection of patients for renal biopsy, a true individual variability-ranging from …

IL-6 is considered one of the well characterized cytokines exhibiting homeostatic, pro-and
anti-inflammatory activities, depending on the receptor variant and the induced intracellular …

Monocyte chemoattractant protein–1 (MCP-1) is a potent chemokine synthesized by several
cell types, eg, inflammatory cells, such as monocytes, and resident renal cells, such as …

Background IgA nephropathy (IgAN) primary glomerulonephritis is characterized by the
deposition of circulating immune complexes composed of polymeric IgA1 molecules with …

Background/Aims: This study was designed to elucidate the clinical significance of serum
uric acid (SUA) and the relationship between hyperuricemia and renal prognosis in IgA …

Urine protein patterns can serve as diagnostic tools in patients with IgA nephropathy.
Background IgA nephropathy (IgAN) is the most common chronic glomerular disease in …