Diagnosis and treatment of metastatic colorectal cancer: a review

LH Biller, D Schrag - Jama, 2021 - jamanetwork.com
Importance Colorectal cancer (CRC) is the third most common cause of cancer mortality
worldwide with more than 1.85 million cases and 850 000 deaths annually. Of new …

[HTML][HTML] Difference between left-sided and right-sided colorectal cancer: a focused review of literature

B Baran, NM Ozupek, NY Tetik, E Acar… - Gastroenterology …, 2018 - ncbi.nlm.nih.gov
Colorectal cancer is the third most common cancer worldwide with a high mortality rate at
the advanced stages. However, colorectal cancer is not a single type of tumor; its …

ACG clinical guidelines: colorectal cancer screening 2021

A Shaukat, CJ Kahi, CA Burke… - Official journal of the …, 2021 - journals.lww.com
Colorectal cancer (CRC) is the third most common cancer in men and women in the United
States. CRC screening efforts are directed toward removal of adenomas and sessile …

Pathways of colorectal carcinogenesis

LH Nguyen, A Goel, DC Chung - Gastroenterology, 2020 - Elsevier
Colorectal cancer is a heterogeneous disease that develops via stepwise accumulation of
well-characterized genetic and epigenetic alterations. We review the genetic changes …

Colorectal cancer development and advances in screening

K Simon - Clinical interventions in aging, 2016 - Taylor & Francis
Most colon tumors develop via a multistep process involving a series of histological,
morphological, and genetic changes that accumulate over time. This has allowed for …

Biomarker-guided therapy for colorectal cancer: strength in complexity

A Sveen, S Kopetz, RA Lothe - Nature Reviews Clinical Oncology, 2020 - nature.com
The number of molecularly stratified treatment options available to patients with colorectal
cancer (CRC) is increasing, with a parallel rise in the use of biomarkers to guide …

Smoking and colorectal cancer risk, overall and by molecular subtypes: a meta-analysis

E Botteri, E Borroni, EK Sloan, V Bagnardi… - Official journal of the …, 2020 - journals.lww.com
METHODS: We conducted a systematic review and meta-analysis of epidemiological
studies on the association between cigarette smoking and CRC risk published up to …

[HTML][HTML] The molecular characteristics of colorectal cancer: Implications for diagnosis and therapy

HT Nguyen, HQ Duong - Oncology letters, 2018 - spandidos-publications.com
Colorectal cancer (CRC) results from the progressive accumulation of multiple genetic and
epigenetic aberrations within cells. The progression from colorectal adenoma to carcinoma …

Mismatch Repair Status and BRAF Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies

S Venderbosch, ID Nagtegaal, TS Maughan… - Clinical Cancer …, 2014 - AACR
Purpose: To determine the prevalence and prognostic value of mismatch repair (MMR)
status and its relation to BRAF mutation (BRAF MT) status in metastatic colorectal cancer …

Emerging trends in colorectal cancer: Dysregulated signaling pathways

R Ahmad, JK Singh, A Wunnava… - International …, 2021 - spandidos-publications.com
Colorectal cancer (CRC) is the third most frequently detected type of cancer, and the second
most common cause of cancer-related mortality globally. The American Cancer Society …