Artesunate, a semisynthetic artemisinin derivative, is well-known and used as the first-line
drug for treating malaria. Apart from treating malaria, artesunate has also been found to …

Artemisinin (ART) and its derivatives have great therapeutical utility as antimalarials and can
be repurposed for other indications, such as viral infections, autoimmune diseases, and …

The ongoing pandemic spread of the severe acute respiratory syndrome coronavirus type 2
(SARS-CoV-2) demands skillful strategies for novel drug development, drug repurposing …

Human cytomegalovirus (HCMV) is a major pathogenic herpesvirus that is prevalent
worldwide and it is associated with a variety of clinical symptoms. Current antiviral therapy …

Drug modification by a fluorescent label is a common tool for studying its mechanism of
action with fluorescence microscopy techniques. However, the attachment of a fluorescent …

Malaria is one of the most widespread diseases worldwide. Besides a growing number of
people potentially threatened by malaria, the consistent emergence of resistance against …

Human cytomegalovirus (HCMV) is a human pathogenic herpesvirus associated with a
variety of clinical symptoms. Current antiviral therapy is not always effective, so that …

Human cytomegalovirus (HCMV) is a near ubiquitous herpesvirus that relies on host cell
metabolism for efficient replication. Although it has been shown that HCMV requires …

The selective formation of ortho-fluoroanilines, representing versatile intermediates for the
pharmaceutical and fine chemical industries, relies to date on, eg, transition-metal-catalyzed …

Currently, the clinically approved repertoire of antiviral drugs predominantly comprises direct-
acting antivirals (DAAs). However, the use of DAAs is frequently limited by adverse effects …