MicroRNAs are small non-coding RNA (18–24 nt long) that fine-tune gene expression at the
post-transcriptional level. With the advent of “multi-omics” analysis and sequencing …

Cryopreservation can help to meet the demand for biosamples of high medical value.
However, it remains difficult to effectively cryopreserve some sensitive cells, tissues, and …

Hypothermia in pediatrics is mainly about small body size. The key thermal factor here is the
large surface-to-volume ratio. Although small mammals, including human infants and …

Hibernation (ie, multiday torpor) is considered an adaptive strategy of mammals to face
seasonal environmental challenges such as food, cold, and/or water shortage. It has been …

Spinal cord injury is a serious disease of the central nervous system involving irreversible
nerve injury and various organ system injuries. At present, no effective clinical treatment …

Evolution has produced animals that survive extreme fluctuations in environmental
conditions including freezing temperatures, anoxia, desiccating conditions, and prolonged …

Proteins are not only the major structural components of living cells but also ensure
essential physiological functions within the organism. Any change in protein abundance …

The critical role microRNAs play in modulating global functions is emerging, both in the
maintenance of homeostatic mechanisms and in the adaptation to diverse environmental …

When food scarcity is coupled with decreased temperatures, gray mouse lemurs
(Microcebus murinus) depress their metabolic rates and retreat into bouts of either daily …

Significance: The ultimate manifestations of life, birth, survival under various environmental
pressures and death are based on bioenergetics. Hibernation is a unique survival strategy …