[HTML][HTML] MicroRNA cues from nature: a roadmap to decipher and combat challenges in human health and disease?
MicroRNAs are small non-coding RNA (18–24 nt long) that fine-tune gene expression at the
post-transcriptional level. With the advent of “multi-omics” analysis and sequencing …
post-transcriptional level. With the advent of “multi-omics” analysis and sequencing …
Bioinspired materials and technology for advanced cryopreservation
M Dou, C Lu, W Rao - Trends in Biotechnology, 2022 - cell.com
Cryopreservation can help to meet the demand for biosamples of high medical value.
However, it remains difficult to effectively cryopreserve some sensitive cells, tissues, and …
However, it remains difficult to effectively cryopreserve some sensitive cells, tissues, and …
[HTML][HTML] Pediatric hypothermia: an ambiguous issue
D Singer - International Journal of Environmental Research and …, 2021 - mdpi.com
Hypothermia in pediatrics is mainly about small body size. The key thermal factor here is the
large surface-to-volume ratio. Although small mammals, including human infants and …
large surface-to-volume ratio. Although small mammals, including human infants and …
[HTML][HTML] Heterothermy as the norm, homeothermy as the exception: variable torpor patterns in the South American marsupial monito del monte (Dromiciops gliroides)
RF Nespolo, C Mejías, A Espinoza… - Frontiers in …, 2021 - frontiersin.org
Hibernation (ie, multiday torpor) is considered an adaptive strategy of mammals to face
seasonal environmental challenges such as food, cold, and/or water shortage. It has been …
seasonal environmental challenges such as food, cold, and/or water shortage. It has been …
[HTML][HTML] The future of artificial hibernation medicine: protection of nerves and organs after spinal cord injury
C Liu, H Yu, Z Li, S Chen, X Li, X Chen… - Neural regeneration …, 2024 - journals.lww.com
Spinal cord injury is a serious disease of the central nervous system involving irreversible
nerve injury and various organ system injuries. At present, no effective clinical treatment …
nerve injury and various organ system injuries. At present, no effective clinical treatment …
Advances and applications of environmental stress adaptation research
LJ Hawkins, KB Storey - Comparative Biochemistry and Physiology Part A …, 2020 - Elsevier
Evolution has produced animals that survive extreme fluctuations in environmental
conditions including freezing temperatures, anoxia, desiccating conditions, and prolonged …
conditions including freezing temperatures, anoxia, desiccating conditions, and prolonged …
[HTML][HTML] Body protein sparing in hibernators: a source for biomedical innovation
Proteins are not only the major structural components of living cells but also ensure
essential physiological functions within the organism. Any change in protein abundance …
essential physiological functions within the organism. Any change in protein abundance …
Role of MicroRNAs in extreme animal survival strategies
The critical role microRNAs play in modulating global functions is emerging, both in the
maintenance of homeostatic mechanisms and in the adaptation to diverse environmental …
maintenance of homeostatic mechanisms and in the adaptation to diverse environmental …
Profiling torpor-responsive microRNAs in muscles of the hibernating primate Microcebus murinus
H Hadj-Moussa, J Zhang, F Pifferi, M Perret… - … et Biophysica Acta (BBA …, 2020 - Elsevier
When food scarcity is coupled with decreased temperatures, gray mouse lemurs
(Microcebus murinus) depress their metabolic rates and retreat into bouts of either daily …
(Microcebus murinus) depress their metabolic rates and retreat into bouts of either daily …
Integrated Redox-Metabolic Orchestration Sustains Life in Hibernating Ground Squirrels
Significance: The ultimate manifestations of life, birth, survival under various environmental
pressures and death are based on bioenergetics. Hibernation is a unique survival strategy …
pressures and death are based on bioenergetics. Hibernation is a unique survival strategy …