SARS-CoV-2-specific immune response and the pathogenesis of COVID-19

E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …

Applications of focused ultrasound in the brain: from thermoablation to drug delivery

Y Meng, K Hynynen, N Lipsman - Nature Reviews Neurology, 2021 - nature.com
Focused ultrasound (FUS) is a disruptive medical technology, and its implementation in the
clinic represents the culmination of decades of research. Lying at the convergence of …

Passage of exogeneous fine particles from the lung into the brain in humans and animals

Y Qi, S Wei, T Xin, C Huang, Y Pu… - Proceedings of the …, 2022 - National Acad Sciences
There are still significant knowledge gaps in understanding the intrusion and retention of
exogeneous particles into the central nervous system (CNS). Here, we uncovered various …

Immunotherapy for glioblastoma: the promise of combination strategies

M Bausart, V Préat, A Malfanti - Journal of Experimental & Clinical Cancer …, 2022 - Springer
Glioblastoma (GBM) treatment has remained almost unchanged for more than 20 years. The
current standard of care involves surgical resection (if possible) followed by concomitant …

How neuroinflammation contributes to neurodegeneration

RM Ransohoff - Science, 2016 - science.org
Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease,
amyotrophic lateral sclerosis, and frontotemporal lobar dementia are among the most …

Lysosomal dysfunction in neurodegeneration: emerging concepts and methods

V Udayar, Y Chen, E Sidransky, R Jagasia - Trends in neurosciences, 2022 - cell.com
The understanding of lysosomes has come a long way since the initial discovery of their role
in degrading cellular waste. The lysosome is now recognized as a highly dynamic organelle …

Blood-brain delivery methods using nanotechnology

DM Teleanu, C Chircov, AM Grumezescu, A Volceanov… - Pharmaceutics, 2018 - mdpi.com
Pathologies of the brain, of which brain cancer, Alzheimer's disease, Parkinson's disease,
stroke, and multiple sclerosis, are some of the most prevalent, and that presently are poorly …

Psychobiotics: mechanisms of action, evaluation methods and effectiveness in applications with food products

M Del Toro-Barbosa, A Hurtado-Romero… - Nutrients, 2020 - mdpi.com
The gut-brain-microbiota axis consists of a bilateral communication system that enables gut
microbes to interact with the brain, and the latter with the gut. Gut bacteria influence …

The blood–brain barrier in psychosis

TA Pollak, S Drndarski, JM Stone, AS David… - The Lancet …, 2018 - thelancet.com
Blood–brain barrier pathology is recognised as a central factor in the development of many
neurological disorders, but much less is known about the role of the blood–brain barrier in …

Western diet: implications for brain function and behavior

I López-Taboada, H González-Pardo… - Frontiers in …, 2020 - frontiersin.org
The Western diet (WD) pattern characterized by high daily intake of saturated fats and
refined carbohydrates often leads to obesity and overweight, and it has been linked to …