Ambient ionization mass spectrometry for point-of-care diagnostics and other clinical measurements

CR Ferreira, KE Yannell, AK Jarmusch, V Pirro… - Clinical …, 2016 - academic.oup.com
BACKGROUND One driving motivation in the development of point-of-care (POC)
diagnostics is to conveniently and immediately provide information upon which healthcare …

Direct ionization methods in mass spectrometry: An overview

CW Klampfl, M Himmelsbach - Analytica chimica acta, 2015 - Elsevier
Within this paper a sub-group of ambient ionization mass spectrometry namely direct
ionization mass spectrometry techniques are reviewed. They are characterized by the …

Ambient ionization and miniature mass spectrometry system for chemical and biological analysis

X Ma, Z Ouyang - TrAC Trends in Analytical Chemistry, 2016 - Elsevier
Ambien ionization and miniaturization of mass spectrometers are two fields in mass
spectrometry that have advanced significantly in the last decade. The integration of the …

Mass spectrometry analysis of drugs of abuse: challenges and emerging strategies

SA Borden, J Palaty, V Termopoli… - Mass spectrometry …, 2020 - Wiley Online Library
Mass spectrometry has been the “gold standard” for drugs of abuse (DoA) analysis for many
decades because of the selectivity and sensitivity it affords. Recent progress in all aspects of …

Analysis of biofluids by paper spray MS: advances and challenges

NE Manicke, BJ Bills, C Zhang - Bioanalysis, 2016 - Future Science
Paper spray MS is part of a cohort of ambient ionization or direct analysis methods that seek
to analyze complex samples without prior sample preparation. Extraction and electrospray …

Direct drug analysis from oral fluid using medical swab touch spray mass spectrometry

V Pirro, AK Jarmusch, M Vincenti, RG Cooks - Analytica Chimica Acta, 2015 - Elsevier
Fourteen common drugs of abuse were identified in spiked oral fluid (ng mL− 1 levels),
analyzed directly from medical swabs using touch spray mass spectrometry (TS-MS) …

Electrospray ionization mass spectrometry with wooden tips: A review

B Hu, ZP Yao - Analytica Chimica Acta, 2022 - Elsevier
Electrospray ionization (ESI) is a powerful ionization technique in mass spectrometry (MS).
There has been an increasing interest for the new development of ESI technique to extend …

Single-use poly (etheretherketone) solid-phase microextraction–transmission mode devices for rapid screening and quantitation of drugs of abuse in oral fluid and …

T Vasiljevic, GA Gomez-Rios, J Pawliszyn - Analytical chemistry, 2018 - ACS Publications
The analysis of oral fluid (OF) and urine samples to detect drug consumption has garnered
considerable attention as alternative biomatrices. Efficient implementation of microextraction …

Ambient ionization mass spectrometry: application and prospective

L Shi, A Habib, L Bi, H Hong, R Begum… - Critical Reviews in …, 2022 - Taylor & Francis
Mass spectrometry (MS) is a formidable analytical tool for the analysis of non-polar to polar
compounds individually and/or from mixtures, providing information on the molecular …

In vivo solid-phase microextraction swab-mass spectrometry for multidimensional analysis of human saliva

L Wu, ZC Yuan, BC Yang, Z Huang, B Hu - Analytica Chimica Acta, 2021 - Elsevier
Solid phase microextraction (SPME) is one of the most powerful sample preparation
techniques for analyte extraction and enrichment from complex matrices. SPME fibers are …