The anti‐inflammatory master regulator IL‐10 is critical to protect the host from tissue
damage during acute phases of immune responses. This regulatory mechanism, central to T …

Sepsis syndrome remains the leading cause of mortality in intensive care units. It is now
believed that along with the body's hyperinflammatory response designated to eliminate the …

Natural killer (NK) cells were first described as immune leukocytes that could kill tumor cells
and soon after were reported to kill virus-infected cells. In the mid-1980s, 10 years after their …

Aging is a progressive degenerative process involving a chronic low-grade inflammation
and the accumulation of senescent cells. One major issue is to reveal the mechanisms …

Sepsis is a syndrome involving systemic inflammation as well as an infectious focus.
Accordingly, the host immune response to sepsis involves complex leukocyte interplay that …

The expression of HLA-G by malignant cells has been proposed as a tumor escape
mechanism from immunosurveillance. However, although the inhibitory effect of HLA-G on …

Introduction During the course of infection, natural killer (NK) cells contribute to innate
immunity by producing cytokines, particularly interferon-gamma (IFN-γ). In addition to their …

Abstract Interleukin-10 (IL-10) is recognized as an anti-inflammatory cytokine that
downmodulates inflammatory immune responses at multiple levels. In innate cells …

Introduction Sepsis is a dysregulated host immune response due to an uncontrolled
infection. It is a leading cause of mortality in adult intensive care units globally. When the …

IL-10 is an anti-inflammatory cytokine that regulates the extent of host immunity to infection
by exerting suppressive effects on different cell types. Herpes viruses induce IL-10 to …