Bone, as a mineralized composite of inorganic (mostly carbonated hydroxyapatite) and
organic (mainly type I collagen) phases, possesses a unique combination of remarkable …

Bone fragility is a major health concern, as the increased risk of bone fractures has
devastating outcomes in terms of mortality, decreased autonomy, and healthcare costs …

Molecular modeling and simulation are invaluable tools for nanoscience that predict
mechanical, physicochemical, and thermodynamic properties of nanomaterials and provide …

The tooth provides an excellent system for deciphering the molecular mechanisms of
organogenesis, and has thus been of longstanding interest to developmental and stem cell …

Calcium phosphate (CaP) materials have a wide range of applications, including
biomaterials, adsorbents, chemical engineering materials, catalysts and catalyst supports …

Calcium orthophosphates are the main mineral constituents of bones and teeth, and there is
great interest in understanding the physical mechanisms that underlie their growth …

Living organisms are capable of inducing the crystallization and deposition of a wide variety
of minerals, 1 but the vertebrates mainly utilize the calcium phosphates in constructing their …

Objectives Remineralization of demineralized dentin is important for improving dentin
bonding stability and controlling primary and secondary caries. Nevertheless, conventional …

Over the last several years, significant progress has been made toward understanding the
mechanisms involved in the mineralization of hard collagenous tissues, such as bone and …

Attachment of dissimilar materials is a major challenge because high levels of localized
stress may develop at their interfaces. An effective biologic solution to this problem exists at …