Species interaction networks are shaped by abiotic and biotic factors. Here, as part of the
Tara Oceans project, we studied the photic zone interactome using environmental factors …

This paper presents new biostatistical methods for the analysis of microbiome data based on
a fully parametric approach using all the data. The Dirichlet-multinomial distribution allows …

There are many instances in genomics data analyses where measurements are made on a
multivariate response. For example, alternative splicing can lead to multiple expressed …

Clinical and environmental meta-omics studies are accumulating an ever-growing amount of
microbial abundance data over a wide range of ecosystems. With a sufficiently large sample …

Gene expression varies widely in natural populations, yet the proximate and ultimate causes
of this variation are poorly known. Understanding how variation in gene expression affects …

DNA is now routinely used in criminal investigations and court cases, although DNA
samples taken at crime scenes are of varying quality and therefore present challenging …

The use of the multinomial logit model is typically restricted to applications with few
predictors, because in high-dimensional settings maximum likelihood estimates tend to …

For more than a decade, music information science and musicology have been at what
Nicholas Cook has described as a'moment of opportunity'for collaboration on database …

Background Clustered regularly-interspaced short palindromic repeats (CRISPR) screens
are usually implemented in cultured cells to identify genes with critical functions. Although …

A simple method to analyze microbiome beta-diversity computes mean beta-diversity
distances from a test sample to standard reference samples. We used reference stool and …