HLA and Sjögren's syndrome susceptibility. A meta-analysis of worldwide studies

P Cruz-Tapias, A Rojas-Villarraga, S Maier-Moore… - Autoimmunity …, 2012 - Elsevier
The aim of this work was to identify common HLA Class II alleles contributing to primary
Sjögren's syndrome (pSS) susceptibility worldwide and to analyze their biological …

Primary Sjögren's syndrome

M Rischmueller, J Tieu, S Lester - Best practice & research Clinical …, 2016 - Elsevier
Primary Sjögren's syndrome (pSS) is a relatively common autoimmune systemic rheumatic
disease. In addition to sicca syndrome and swollen salivary glands, systemic features …

Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome

JE Gottenberg, N Cagnard… - Proceedings of the …, 2006 - National Acad Sciences
Gene expression analysis of target organs might help provide new insights into the
pathogenesis of autoimmune diseases. We used global gene expression profiling of minor …

Update on pathogenesis of Sjogren's syndrome

P Sandhya, B Theyilamannil Kurien… - Current …, 2017 - ingentaconnect.com
Sjogren's syndrome is a common autoimmune disease that presents with sicca symptoms
and extraglandular features. Sjogren's syndrome is presumably as common as RA; yet it is …

In primary Sjögren's syndrome, HLA class II is associated exclusively with autoantibody production and spreading of the autoimmune response

JE Gottenberg, M Busson, P Loiseau… - … : Official Journal of …, 2003 - Wiley Online Library
Objective. To reevaluate, in a large series of patients with Sjögren's syndrome (SS) recruited
from 2 French centers, the question of whether HLA is associated with SS itself or with a …

The meaning of anti-Ro and anti-La antibodies in primary Sjögren's syndrome

G Hernández-Molina, G Leal-Alegre… - Autoimmunity …, 2011 - Elsevier
Anti-SSA/Ro and anti-La/SSB are the hallmark antibodies in primary Sjögren's syndrome
(pSS), being present in 60–70%. These antibodies have been associated with an earlier …

Cow's milk and type 1 diabetes: the real debate is about mucosal immune function.

LC Harrison, MC Honeyman - Diabetes, 1999 - Am Diabetes Assoc
The hypothesis that early exposure of the infant to cow's milk (or lack of breast-feeding)
predisposes the child to type 1 diabetes dates from the 1980s. It has important implications …

Current issues in Sjögren's syndrome

R Jonsson, K Moen, D Vestrheim, P Szodoray - Oral diseases, 2002 - Wiley Online Library
Sjögren's syndrome is a chronic autoimmune and rheumatic disorder with prominent sicca
complaints from the mucous membranes because of lack of proper exocrine secretions …

Genetic aspects of Sjögren's syndrome

AI Bolstad, R Jonsson - Arthritis Research & Therapy, 2002 - Springer
Sjögren's syndrome is a multisystem inflammatory rheumatic disease that is classified into
primary and secondary forms, with cardinal features in the eye (keratoconjunctivitis sicca) …

Anti-Ro60 and anti-Ro52/TRIM21: Two distinct autoantibodies in systemic autoimmune diseases

AYS Lee, JH Reed, TP Gordon - Journal of Autoimmunity, 2021 - Elsevier
As iconic and important diagnostic autoantibodies, anti-Ro60 and anti-Ro52/tri-partite motif-
containing 21 (TRIM21) make a common appearance in a number of systemic autoimmune …