Microbiota can significantly contribute to colorectal cancer initiation and development. It was
described that E. coli harbouring polyketide synthase (pks) genes can synthetize bacterial …

Klebsiella pneumoniae is a Gram-negative bacterium capable of colonizing, invading, and
causing infections in different anatomical sites of the human body. Its ability to evade the …

Uropathogenic Escherichia coli (UPEC) is the most common causative agent of urinary tract
infections worldwide. The pathogenicity of UPEC was found to be related to expression of …

Escherichia coli is a multifaceted microbe since some are commensals, normally inhabiting
the gut of both humans and animals while others are pathogenic responsible for a wide …

Background Probiotics have gained attention for their potential maintaining gut and immune
homeostasis. They have been found to confer protection against pathogen colonization …

Abstract Background Uropathogenic Escherichia coli (UPEC) is the main etiological agent
behind community-acquired and hospital-acquired urinary tract infections (UTIs), which are …

The bacterial genotoxin colibactin interferes with the eukaryotic cell cycle by causing dsDNA
breaks. It has been linked to bacterially induced colorectal cancer in humans. Colibactin is …

The genotoxin colibactin is a secondary metabolite produced by the polyketide synthase
(pks) island harbored by extraintestinal pathogenic E. coli (ExPEC) and other members of …

Environmental factors like the pathogenicity island polyketide synthase positive (pks+)
Escherichia coli (E. coli) could have potential for risk stratification in colorectal cancer (CRC) …

Covering: 2015 to 2020 The field of natural products is dominated by a discovery paradigm
that follows the sequence: isolation, structure elucidation, chemical synthesis, and then …