Abbreviations: AASLD, American Association for the Study of Liver Diseases; AI, artificial
intelligence; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUROC …

Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum of clinical and
histopathological changes including “simple” steatosis, steatosis with inflammation …

Background Nonalcoholic fatty disease (NAFLD) is the most common liver disease, since it
is strongly associated with obesity and metabolic syndrome pandemics. NAFLD may affect …

Idiosyncratic (unpredictable) drug-induced liver injury is one of the most challenging liver
disorders faced by hepatologists, because of the myriad of drugs used in clinical practice …

Idiosyncratic drug-induced liver injury mimics acute and chronic liver disease. It is under
recognized and underrecognised because of the lack of pathognomonic diagnostic …

Nonalcoholic fatty liver disease (NAFLD) is a leading cause of liver disease in developed
countries. Its frequency is increasing in the general population mostly due to the widespread …

Cell-based high-content screening (HCS) assays have become an increasingly attractive
alternative to traditional in vitro and in vivo testing in pharmaceutical drug development and …

Lipid droplets (LDs) are lipid-abundant organelles found in most cell lines and primarily
consist of neutral lipids. They serve as a repository of various lipids and are associated with …

Aliment Pharmacol Ther 2010; 32: 3–13 Summary Background Drug‐induced liver injury
(DILI) is an important differential diagnosis in many patients in clinical hepatology. DILI is the …

Fatty liver disease is a common lipid metabolism disorder influenced by the combination of
individual genetic makeup, drug exposure, and life-style choices that are frequently …