Novel insights into atopic dermatitis

CF Schuler IV, AC Billi, E Maverakis, LC Tsoi… - Journal of Allergy and …, 2023 - Elsevier
Recent research into the pathophysiology and treatment of atopic dermatitis (AD) has shown
notable progress. An increasing number of aspects of the immune system are being …

Reporting of observational studies explicitly aiming to emulate randomized trials: a systematic review

HJ Hansford, AG Cashin, MD Jones… - JAMA network …, 2023 - jamanetwork.com
Importance Observational (nonexperimental) studies that aim to emulate a randomized trial
(ie, the target trial) are increasingly informing medical and policy decision-making, but it is …

Expert consensus on the systemic treatment of atopic dermatitis in special populations

DN Adam, MJ Gooderham, JR Beecker… - Journal of the …, 2023 - Wiley Online Library
With the increasing number of options for the treatment of moderate‐to‐severe atopic
dermatitis, clinicians need guidance on a practical approach to selecting a systemic agent …

Conjunctivitis in adult patients with moderate‐to‐severe atopic dermatitis: results from five tralokinumab clinical trials

A Wollenberg, LA Beck… - British Journal of …, 2022 - academic.oup.com
Background Tralokinumab, a fully human IgG4 monoclonal antibody that specifically binds
with high affinity to interleukin‐13, effectively reduces moderate‐to‐severe atopic dermatitis …

Safety of tralokinumab in adult patients with moderate‐to‐severe atopic dermatitis: pooled analysis of five randomized, double‐blind, placebo‐controlled phase II and …

EL Simpson, JF Merola, JI Silverberg… - British Journal of …, 2022 - academic.oup.com
Background Tralokinumab is a fully human monoclonal antibody that neutralizes the activity
of interleukin‐13, a key pathogenic driver of atopic dermatitis (AD). Clinical trials including …

Dupilumab ocular side effects in patients with atopic dermatitis: a systematic review

N Neagu, C Dianzani, G Avallone… - Journal of the …, 2022 - Wiley Online Library
Atopic dermatitis (AD) is a chronic, inflammatory skin disorder that most frequently occurs in
children, but it can also affect adults. Even though most AD cases can be managed with …

Impact of a decade of research into atopic dermatitis

PD Arkwright, JJ Koplin - The Journal of Allergy and Clinical Immunology …, 2023 - Elsevier
The last decade has seen an unprecedented pace of change, particularly of clinical
research in atopic dermatitis (AD). This review summarizes some key discoveries. Over the …

Association of self-reported high-risk allergy history with allergy symptoms after COVID-19 vaccination

L Li, LB Robinson, R Patel, AB Landman… - JAMA Network …, 2021 - jamanetwork.com
Importance Allergic history in individuals with confirmed anaphylaxis to a messenger RNA
(mRNA) COVID-19 vaccine is common. However, the risk factors for allergy symptoms after …

Dupilumab‐associated ocular surface disease in atopic dermatitis patients: Clinical characteristics, ophthalmic treatment response and conjunctival goblet cell …

R Achten, J Thijs, M van Der Wal, C van Luijk… - Allergy, 2023 - Wiley Online Library
Background Dupilumab‐associated ocular surface disease (DAOSD) is frequently reported
as side effect in atopic dermatitis (AD) patients. Therefore, the aim of this study was to …

[HTML][HTML] Advances in atopic dermatitis

A Plant, MR Ardern-Jones - Clinical Medicine, 2021 - Elsevier
Atopic dermatitis (AD) is a common inflammatory skin disease characterised by itch and is
responsible for significant reduction in quality of life. While AD primarily arises in those …