Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis
Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …
and contribute to the development of novel diagnostic and therapeutic strategies to further …
Biological Properties of Vitamins of the B-Complex, Part 1: Vitamins B1, B2, B3, and B5
M Hrubša, T Siatka, I Nejmanová, M Vopršalová… - Nutrients, 2022 - mdpi.com
This review summarizes the current knowledge on essential vitamins B1, B2, B3, and B5.
These B-complex vitamins must be taken from diet, with the exception of vitamin B3, that can …
These B-complex vitamins must be taken from diet, with the exception of vitamin B3, that can …
Structure of the human lipid exporter ABCA1
ABCA1, an ATP-binding cassette (ABC) subfamily A exporter, mediates the cellular efflux of
phospholipids and cholesterol to the extracellular acceptor apolipoprotein AI (apoA-I) for …
phospholipids and cholesterol to the extracellular acceptor apolipoprotein AI (apoA-I) for …
ABC transporters: human disease and pharmacotherapeutic potential
Adenosine triphosphate (ATP)-binding cassette (ABC) transporters are a 48-member
superfamily of membrane proteins that actively transport a variety of biological substrates …
superfamily of membrane proteins that actively transport a variety of biological substrates …
Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses
Atherosclerosis has been characterized as a chronic inflammatory response to cholesterol
deposition in arteries, but the mechanisms linking cholesterol accumulation in macrophage …
deposition in arteries, but the mechanisms linking cholesterol accumulation in macrophage …
Cholesterol transport system: an integrated cholesterol transport model involved in atherosclerosis
XH Yu, DW Zhang, XL Zheng, CK Tang - Progress in Lipid Research, 2019 - Elsevier
Atherosclerosis, the pathological basis of most cardiovascular disease (CVD), is closely
associated with cholesterol accumulation in the arterial intima. Excessive cholesterol is …
associated with cholesterol accumulation in the arterial intima. Excessive cholesterol is …
HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol export
XM Du, MJ Kim, L Hou, W Le Goff… - Circulation …, 2015 - Am Heart Assoc
Rationale: High-density lipoprotein (HDL) is a heterogeneous population of particles.
Differences in the capacities of HDL subfractions to remove cellular cholesterol may explain …
Differences in the capacities of HDL subfractions to remove cellular cholesterol may explain …
ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins
The mechanisms responsible for the inverse relationship between plasma high-density
lipoprotein (HDL) levels and atherosclerotic cardiovascular disease are poorly understood …
lipoprotein (HDL) levels and atherosclerotic cardiovascular disease are poorly understood …
Functionally defective high-density lipoprotein: a new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosis
A Kontush, MJ Chapman - Pharmacological reviews, 2006 - ASPET
High-density lipoproteins (HDL) possess key atheroprotective biological properties,
including cellular cholesterol efflux capacity, and anti-oxidative and anti-inflammatory …
including cellular cholesterol efflux capacity, and anti-oxidative and anti-inflammatory …
HDL cholesterol and protective factors in atherosclerosis
G Assmann, AM Gotto Jr - Circulation, 2004 - Am Heart Assoc
A low level of high-density lipoprotein cholesterol (HDL-C) is an important risk factor for
cardiovascular disease. Epidemiological and clinical studies provide evidence that HDL-C …
cardiovascular disease. Epidemiological and clinical studies provide evidence that HDL-C …