Serum prolactin (PRL) levels exhibit a gradual rise both in male and female rats from birth to
adulthood, with females consistently displaying higher levels compared to age-matched …

Berberine chloride (BBR) is an isoquinoline derivative alkaloid isolated from medicinal
herbs, including Coptis chinensis and Berberis aristate. This compound plays significant …

Endometrial carcinoma (EC), an estrogen-dependent gynecological malignancy, is
prevalent worldwide. Estrogen receptor α (ERα) and estrogen receptor β (ERβ) are two main …

Ovarian steroids control a variety of physiological functions. They exert actions through
classical nuclear steroid receptors, but rapid non-genomic actions through specific …

Humans are exposed to numerous endocrine disruptors on a daily basis, which may
interfere with endogenous estrogens, with Di-(2-ethylhexyl) phthalate (DEHP) being one of …

Phthalates are synthetic chemicals widely used to make polyvinylchloride (PVC) soft and
flexible. Of these, Di-(2-ethylhexyl) phthalate (DEHP) is the most commonly used, with high …

Membrane progesterone receptors are known to mediate rapid nongenomic progesterone
effects in different cell types. Recent evidence revealed that mPRα is highly expressed in the …

In this study, we focused on ERβ regulation in the adenohypophysis under different
estrogenic milieu, by analyzing whether ER modulates the phosphatase and tensin homolog …

The molecular mechanisms underlying the ERα nuclear/cytoplasmic pool that modulates
pituitary cell proliferation have been widely described, but it is still not clear how ERα is …

The canine corpus luteum (CL) is able to synthetise, activate and deactivate 17b-estradiol
(E2) and also expresses nuclear estrogen receptors in a time-dependent manner during …