Systemic amyloidosis is a rare protein misfolding and deposition disorder leading to
progressive organ failure. There are over 15 types of systemic amyloidosis, each caused by …

Transthyretin cardiac amyloidosis (ATTR-CA) is increasingly diagnosed owing to the
emergence of noninvasive imaging and improved awareness. Clinical penetrance of …

Cardiac amyloidosis is a serious and progressive infiltrative disease that is caused by the
deposition of amyloid fibrils at the cardiac level. It can be due to rare genetic variants in the …

Cardiac amyloidosis is a serious and progressive infiltrative disease that is caused by the
deposition of amyloid fibrils at the cardiac level. It can be due to rare genetic variants in the …

Often considered a rare disease, cardiac amyloidosis is increasingly recognized by
practicing clinicians. The increased rate of diagnosis is in part due the aging of the …

Aims In patients with transthyretin amyloid cardiomyopathy (ATTR-CM), the effect of
tafamidis on myocardial function using serial speckle tracking echocardiography has not …

Aims Transthyretin amyloid cardiomyopathy (ATTR‐CM) is an increasingly diagnosed
disease. Echocardiography is widely utilized, but studies to confirm the value of …

Transthyretin (TTR) is a tetrameric protein synthesized primarily by the liver. TTR can misfold
into pathogenic ATTR amyloid fibrils that deposit in the nerves and heart, causing a …

Importance Systemic amyloidosis from transthyretin (ATTR) protein is the most common type
of amyloidosis that causes cardiomyopathy. Observations Transthyretin (TTR) protein …

Transthyretin (TTR) is a tetrameric protein found in human plasma and cerebrospinal fluid
that functions as a transporter of thyroxine (T4) and retinol. A mutation resulting in the …