Toward telomere-to-telomere cat genomes for precision medicine and conservation biology

WJ Murphy, AJ Harris - Genome Research, 2024 - genome.cshlp.org
Genomic data from species of the cat family Felidae promise to stimulate veterinary and
human medical advances, and clarify the coherence of genome organization. We describe …

Precision medicine using whole genome sequencing identifies a novel dystrophin (DMD) variant for X‐linked muscular dystrophy in a cat

GD Shelton, F Tucciarone, LT Guo… - Journal of Veterinary …, 2024 - Wiley Online Library
Abstract Background Muscular dystrophies (MDs) are a large, heterogeneous group of
degenerative muscle diseases. X‐linked dystrophin‐deficient MD in cats is the first …

Genetic Testing: practical dos and don'ts for cats

LA Lyons - Journal of Feline Medicine and Surgery, 2024 - journals.sagepub.com
Practical relevance: A significant number of genetic variants are known for domestic cats
and their breeds. Several DNA variants are causal for inherited diseases and most of the …

An ancient haplotype containing antimicrobial peptide gene variants is associated with severe fungal skin disease in Persian cats

AN Myers, SD Lawhon, AB Diesel, CW Bradley… - PLoS …, 2022 - journals.plos.org
Dermatophytosis, also known as ringworm, is a contagious fungal skin disease affecting
humans and animals worldwide. Persian cats exhibit severe forms of the disease more …

A Nonsense Variant in the DMD Gene Causes X-Linked Muscular Dystrophy in the Maine Coon Cat

E Beckers, I Cornelis, SFM Bhatti, P Smets, GD Shelton… - Animals, 2022 - mdpi.com
Simple Summary Muscular dystrophy (MD) in cats is a muscular disease that can have a
fatal outcome. It is often caused by variants in the DMD gene and shows an X-linked …

[HTML][HTML] Beta-mannosidosis in a domestic cat associated with a missense variant in MANBA

ML Katz, J Cook, CH Vite, RS Campbell, LM Coghill… - Gene, 2024 - Elsevier
A 6-month-old cat of unknown ancestry presented for a neurologic evaluation due to
progressive motor impairment. Complete physical and neurologic examinations suggested …

The TNNT2:c.95‐108G>A variant is common in Maine Coons and shows no association with hypertrophic cardiomyopathy

T Schipper, Å Ohlsson, M Longeri, JJ Hayward… - Animal …, 2022 - Wiley Online Library
Hypertrophic cardiomyopathy (HCM) is a common and potentially fatal heart disease in
many cat breeds. An intronic variant in TNNT2, c. 95‐108G> A, was recently reported as the …

Possibilities of skin coat color‐dependent risks and risk factors of squamous cell carcinoma and deafness of domestic cats inferred via RNA‐seq data

A Awazu, D Takemoto, K Watanabe… - Genes to Cells, 2023 - Wiley Online Library
The transcriptome data of skin cells from domestic cats with brown, orange, and white coats
were analyzed using a public database to investigate the possible relationship between coat …

Genomic regions associated with coat color in Gir cattle

SVSA Maciel, IPP Oliveira, BB Senes, JAIIV Silva… - …, 2024 - cdnsciencepub.com
Indicine cattle breeds are adapted to the tropical climate, and their coat plays an important
role in this process. Coat color influences thermoregulation and the adhesion of …

Developmental lung disease in a cat associated with high probability of severe pulmonary hypertension: natural history, histopathology and genetic analysis

Y Nebel, K Williams, LA Lyons… - Journal of Feline …, 2024 - journals.sagepub.com
Case summary This report describes the diagnostic findings, natural history and genetic
analysis of the candidate gene Forkhead Box F1 (FOXF1) in a young cat with developmental …