Reactive oxygen species (ROS)-responsive prodrugs, probes, and theranostic prodrugs: applications in the ROS-related diseases
P Wang, Q Gong, J Hu, X Li… - Journal of Medicinal …, 2020 - ACS Publications
Elevated levels of reactive oxygen species (ROS) have commonly been implicated in a
variety of diseases, including cancer, inflammation, and neurodegenerative diseases. In …
variety of diseases, including cancer, inflammation, and neurodegenerative diseases. In …
Stimuli-responsive boron-based materials in drug delivery
BC Das, P Chokkalingam, P Masilamani… - International Journal of …, 2023 - mdpi.com
Drug delivery systems, which use components at the nanoscale level as diagnostic tools or
to release therapeutic drugs to particular target areas in a regulated manner, are a fast …
to release therapeutic drugs to particular target areas in a regulated manner, are a fast …
Reactive oxygen species (ROS)-responsive nanoprobe for bioimaging and targeting therapy of osteoarthritis
C Shen, M Gao, H Chen, Y Zhan, Q Lan, Z Li… - Journal of …, 2021 - Springer
Stimulus-responsive therapy that allows precise imaging-guided therapy is limited for
osteoarthritis (OA) therapy due to the selection of proper physiological markers as stimulus …
osteoarthritis (OA) therapy due to the selection of proper physiological markers as stimulus …
Prodrug strategies for targeted therapy triggered by reactive oxygen species
JP Cadahía, V Previtali, NS Troelsen, MH Clausen - MedChemComm, 2019 - pubs.rsc.org
Increased levels of reactive oxygen species (ROS) have been associated with numerous
pathophysiological conditions including cancer and inflammation and the ROS stimulus …
pathophysiological conditions including cancer and inflammation and the ROS stimulus …
Natural morin-based metal organic framework nanoenzymes modulate articular cavity microenvironment to alleviate osteoarthritis
J Cai, L Liu, Z Qin, S Liu, Y Wang, Z Chen, Y Yao… - Research, 2023 - spj.science.org
Osteoarthritis (OA) is always characterized as excessive reactive oxygen species (ROS)
inside articular cavity. Mimicking natural metalloenzymes with metal ions as the active …
inside articular cavity. Mimicking natural metalloenzymes with metal ions as the active …
Sensors, imaging agents, and theranostics to help understand and treat reactive oxygen species related diseases
KC Yan, AC Sedgwick, Y Zang, GR Chen… - Small …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) consist of a diverse range of oxidative small molecular ions
and free radicals that are produced throughout the body during certain biological processes …
and free radicals that are produced throughout the body during certain biological processes …
Folate receptor-targeting and reactive oxygen species-responsive liposomal formulation of methotrexate for treatment of rheumatoid arthritis
M Chen, KA Daddy JC, Z Su, NEI Guissi, Y Xiao… - Pharmaceutics, 2019 - mdpi.com
Multifunctional nanomedicines with active targeting and stimuli-responsive drug release
function utilizing pathophysiological features of the disease are regarded as an effective …
function utilizing pathophysiological features of the disease are regarded as an effective …
Nanomedicines for improved targetability to inflamed synovium for treatment of rheumatoid arthritis: multi-functionalization as an emerging strategy to optimize …
G Fang, Q Zhang, Y Pang, HE Thu, Z Hussain - Journal of Controlled …, 2019 - Elsevier
Owing to its intricate autoimmune pathophysiology and significant risks of progression to
other rheumatic co-morbidities (ie, osteoporosis and osteoarthritis), a plausible therapeutic …
other rheumatic co-morbidities (ie, osteoporosis and osteoarthritis), a plausible therapeutic …
Enzymatically crosslinked tyramine-gellan gum hydrogels as drug delivery system for rheumatoid arthritis treatment
IM Oliveira, C Goncalves, ME Shin, S Lee… - Drug Delivery and …, 2021 - Springer
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by joint synovial
inflammation, as well as cartilage and bone tissue destruction. Current strategies for the …
inflammation, as well as cartilage and bone tissue destruction. Current strategies for the …
Structure modification: a successful tool for prodrug design
Y Cheng, C Zhong, S Yan, C Chen… - Future Medicinal …, 2023 - Taylor & Francis
Prodrug strategy is critical for innovative drug development. Structural modification is the
most straightforward and effective method to develop prodrugs. Improving drug defects and …
most straightforward and effective method to develop prodrugs. Improving drug defects and …