[PDF][PDF] Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
D Liebschner, PV Afonine, ML Baker… - … Section D: Structural …, 2019 - journals.iucr.org
Diffraction (X-ray, neutron and electron) and electron cryo-microscopy are powerful methods
to determine three-dimensional macromolecular structures, which are required to …
to determine three-dimensional macromolecular structures, which are required to …
Challenges and opportunities in cryo-EM single-particle analysis
D Lyumkis - Journal of Biological Chemistry, 2019 - ASBMB
Cryogenic electron microscopy (cryo-EM) enables structure determination of
macromolecular objects and their assemblies. Although the techniques have been …
macromolecular objects and their assemblies. Although the techniques have been …
Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement
M McCallum, N Czudnochowski, LE Rosen, SK Zepeda… - Science, 2022 - science.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern evades antibody-mediated immunity that comes from vaccination or infection with …
concern evades antibody-mediated immunity that comes from vaccination or infection with …
SARS-CoV-2 immune evasion by the B. 1.427/B. 1.429 variant of concern
A novel variant of concern (VOC) named CAL. 20C (B. 1.427/B. 1.429), which was originally
detected in California, carries spike glycoprotein mutations S13I in the signal peptide …
detected in California, carries spike glycoprotein mutations S13I in the signal peptide …
[HTML][HTML] Increased resistance of SARS-CoV-2 variant P. 1 to antibody neutralization
The emergence of SARS-CoV-2 variants has raised concerns about altered sensitivity to
antibody-mediated immunity. The relative resistance of SARS-CoV-2 variants B. 1.1. 7 and …
antibody-mediated immunity. The relative resistance of SARS-CoV-2 variants B. 1.1. 7 and …
Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission leads to the
emergence of variants, including the B. 1.617. 2 (Delta) variant of concern that is causing a …
emergence of variants, including the B. 1.617. 2 (Delta) variant of concern that is causing a …
Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite
Numerous antibodies that neutralize SARS-CoV-2 have been identified, and these generally
target either the receptor-binding domain (RBD) or the N-terminal domain (NTD) of the viral …
target either the receptor-binding domain (RBD) or the N-terminal domain (NTD) of the viral …
Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology
Analysis of the specificity and kinetics of neutralizing antibodies (nAbs) elicited by SARS-
CoV-2 infection is crucial for understanding immune protection and identifying targets for …
CoV-2 infection is crucial for understanding immune protection and identifying targets for …
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
L Cao, I Goreshnik, B Coventry, JB Case, L Miller… - Science, 2020 - science.org
Targeting the interaction between the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) spike protein and the human angiotensin-converting enzyme 2 (ACE2) …
(SARS-CoV-2) spike protein and the human angiotensin-converting enzyme 2 (ACE2) …
Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic continues,
with devasting consequences for human lives and the global economy,. The discovery and …
with devasting consequences for human lives and the global economy,. The discovery and …