Resveratrol-mediated regulation of mitochondria biogenesis-associated pathways in neurodegenerative diseases: Molecular insights and potential therapeutic …

A Shaito, M Al-Mansoob, SMS Ahmad… - Current …, 2023 - benthamdirect.com
Neurodegenerative disorders include different neurological conditions that affect nerve cells,
causing the progressive loss of their functions and ultimately leading to loss of mobility …

Telomerase: a prominent oncological target for development of chemotherapeutic agents

K Vishwakarma, R Dey, H Bhatt - European Journal of Medicinal Chemistry, 2023 - Elsevier
Telomerase is a ribonucleoprotein (RNP) responsible for the maintenance of chromosomal
integrity by stabilizing telomere length. Telomerase is a widely expressed hallmark …

Biological effects of licochalcones

GD Maria Pia, F Sara, F Mario… - Mini reviews in …, 2019 - ingentaconnect.com
Medicinal plants and their natural bioactive molecules, are evaluated as the foundation for
health preservation and care of humanity. The licorice root, known as “Radix Glycyrrhizae” …

[HTML][HTML] Advancements in Telomerase-Targeted Therapies for Glioblastoma: A Systematic Review

G Pennisi, P Bruzzaniti, B Burattini… - International Journal of …, 2024 - mdpi.com
Glioblastoma (GBM) is a primary CNS tumor that is highly lethal in adults and has limited
treatment options. Despite advancements in understanding the GBM biology, the standard …

Stilbene compounds inhibit tumor growth by the induction of cellular senescence and the inhibition of telomerase activity

YH Lee, YY Chen, YL Yeh, YJ Wang… - International journal of …, 2019 - mdpi.com
Cellular senescence is a state of cell cycle arrest characterized by a distinct morphology,
gene expression pattern, and secretory phenotype. It can be triggered by multiple …

Telomerase inhibition in malignant gliomas: A systematic review

QG D'Alessandris, M Battistelli, G Pennisi… - Expert reviews in …, 2023 - cambridge.org
Glioblastoma (GBM) is the most frequent adult malignant brain tumour and despite different
therapeutic efforts, the median overall survival still ranges from 14 to 18 months. Thus, new …

Bioactive phenolic compounds in the modulation of central and peripheral nervous system cancers: Facts and misdeeds

L Perrone, S Sampaolo, MAB Melone - Cancers, 2020 - mdpi.com
Efficacious therapies are not available for the cure of both gliomas and glioneuronal tumors,
which represent the most numerous and heterogeneous primary cancers of the central …

[PDF][PDF] Resveratrol as a potential broad-spectrum compound for cancer treatment

LKS Tan, CW How, JB Foo… - … In Microbes & …, 2020 - journals.hh-publisher.com
Resveratrol as a potential broad-spectrum compound for cancer treatment Page 1 Progress in
Microbes and Molecular Biology Review Article 1 Resveratrol as a potential broad-spectrum …

Protective effect of resveratrol against glioblastoma: a review

M Ashrafizadeh, R Mohammadinejad… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
Background: One of the most common tumors of the central nervous system is Glioblastoma
(GBM). Objective: There is not still an appropriate cure for this malignant tumor. Plant …

Resveratrol and cancer cell biology

CK Singh, G Chhabra, N Ahmad - … : State-of-the-Art science and …, 2019 - World Scientific
Recent advances in cancer biology have resulted in a near-complete information regarding
the major pathways involved in cancer development and progression. This has resulted in …