Update on the pathophysiology and medical treatment of peripheral artery disease

J Golledge - Nature reviews cardiology, 2022 - nature.com
Approximately 6% of adults worldwide have atherosclerosis and thrombosis of the lower
limb arteries (peripheral artery disease (PAD)) and the prevalence is rising. PAD causes leg …

Winners do what they fear: exercise and peripheral arterial disease—an umbrella review

S Peñín-Grandes, S López-Ortiz… - European Journal of …, 2024 - academic.oup.com
Aims This systematic review aims to evaluate and summarize findings from published meta-
analyses on the effects of regular exercise in patients with peripheral arterial disease (PAD) …

Transcriptomic and proteomic of gastrocnemius muscle in peripheral artery disease

L Ferrucci, J Candia, C Ubaida-Mohien… - Circulation …, 2023 - Am Heart Assoc
Background: Few effective therapies exist to improve lower extremity muscle pathology and
mobility loss due to peripheral artery disease (PAD), in part because mechanisms …

Exercise therapy for chronic symptomatic peripheral artery disease: A clinical consensus document of the European Society of Cardiology Working Group on Aorta …

L Mazzolai, J Belch, M Venermo… - European Heart …, 2024 - academic.oup.com
All guidelines worldwide strongly recommend exercise as a pillar of the management of
patients affected by lower extremity peripheral artery disease (PAD). Exercise therapy in this …

[HTML][HTML] Sit to stand muscle power is related to functional performance at baseline and after supervised exercise training in patients with lower extremity peripheral …

S Lanzi, A Pousaz, L Calanca, L Mazzolai - European Journal of Vascular …, 2023 - Elsevier
Objective Patients with peripheral artery disease (PAD) have decreased muscle power
contributing to functional limitations. The sit-to-stand (STS) is a validated test to assess …

2024 ACC/AHA/AACVPR/APMA/ABC/SCAI/SVM/SVN/SVS/SIR/VESS guideline for the management of lower extremity peripheral artery disease: a report of the …

WC Members, HL Gornik, HD Aronow… - Journal of the American …, 2024 - Elsevier
Abstract Aim The “2024 ACC/AHA/AACVPR/APMA/ABC/SCAI/SVM/SVN/SVS/SIR/VESS
Guideline for the Management of Lower Extremity Peripheral Artery Disease” provides …

Diabetes mellitus in peripheral artery disease: Beyond a risk factor

MV Singh, AO Dokun - Frontiers in cardiovascular medicine, 2023 - frontiersin.org
Peripheral artery disease (PAD) is one of the major cardiovascular diseases that afflicts a
large population worldwide. PAD results from occlusion of the peripheral arteries of the …

[HTML][HTML] Management of peripheral arterial disease: lifestyle modifications and medical therapies

RW King, ME Canonico, MP Bonaca… - Journal of the Society for …, 2022 - Elsevier
Peripheral artery disease (PAD) commonly refers to atherosclerotic narrowing of
noncoronary arteries, primarily those supplying the lower extremities. The risk factors for …

[HTML][HTML] Pseudoxanthoma elasticum–Genetics, Pathophysiology, and Clinical Presentation

K Pfau, I Lengyel, J Ossewaarde-van Norel… - Progress in Retinal and …, 2024 - Elsevier
Pseudoxanthoma elasticum (PXE) is an autosomal-recessively inherited multisystem
disease. Mutations in the ABCC6-gene are causative, coding for a transmembrane …

[HTML][HTML] Exercise and Ischemia-Activated Pathways in Limb Muscle Angiogenesis and Vascular Regeneration

VA Narkar - Methodist DeBakey Cardiovascular Journal, 2023 - ncbi.nlm.nih.gov
Exercise has a profound effect on cardiovascular disease, particularly through vascular
remodeling and regeneration. Peripheral artery disease (PAD) is one such cardiovascular …