Purpose Nonlocal mean (NLM) filtering proved to be an effective tool for noise reduction in
natural and medical imaging. The technique relies on existing redundant information in the …

PET/CT has become a preferred imaging modality over PET-only scanners in clinical
practice. However, along with the significant improvement in diagnostic accuracy and patient …

PET images commonly suffer from the high noise level and poor signal-to-noise ratio (SNR),
thus adversely impacting lesion detectability and quantitative accuracy. In this work, a novel …

Positron emission tomography (PET) imaging allows for measurement of activity
concentrations of a given radiotracer in vivo. The quantitative capabilities of PET imaging …

Response Evaluation Criteria in Prostate-Specific Membrane Antigen Imaging (RECIP) 1.0
is an evidence-based framework to evaluate therapeutic efficacy in metastatic prostate …

The effective elimination of noise from the original image has emerged as a hard nut to crack
for the researchers. The hunt for effective image denoising techniques continues to be a …

Noise is an unwanted entity that corrupts the image due to which its quality degrades. This
degradation may be suppressing details like edges, ridges, and other fine structures that are …

Purpose: Because of high diagnostic accuracy and fast scan time, computed tomography
(CT) has been widely used in various clinical applications. Since the CT scan introduces …

REPLY: We appreciate the opportunity to respond to the commentary on our paper (1) by Dr.
Beattie and to offer additional perspective on the topic of artificial intelligence (AI)–based …

Positron emission tomography (PET) imaging is widely used in nuclear medicine. However,
data acquired by a PET system are generally contaminated with heavy noise, which often …