Aging and aging-related diseases: from molecular mechanisms to interventions and treatments

J Guo, X Huang, L Dou, M Yan, T Shen… - Signal Transduction and …, 2022 - nature.com
Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …

Indoor air pollution, related human diseases, and recent trends in the control and improvement of indoor air quality

VV Tran, D Park, YC Lee - … journal of environmental research and public …, 2020 - mdpi.com
Indoor air pollution (IAP) is a serious threat to human health, causing millions of deaths each
year. A plethora of pollutants can result in IAP; therefore, it is very important to identify their …

The impact of ageing on monocytes and macrophages

RPH De Maeyer, ES Chambers - Immunology letters, 2021 - Elsevier
Ageing is a global burden. Increasing age is associated with increased incidence of
infections and cancer and decreased vaccine efficacy. This increased morbidity observed …

Mechanisms of lung damage and development of COPD due to household biomass-smoke exposure: inflammation, oxidative stress, MicroRNAs, and gene …

B Ortiz-Quintero, I Martínez-Espinosa, R Pérez-Padilla - Cells, 2022 - mdpi.com
Chronic exposure to indoor biomass smoke from the combustion of solid organic fuels is a
major cause of disease burden worldwide. Almost 3 billion people use solid fuels such as …

The cGAS‐STING pathway: the role of self‐DNA sensing in inflammatory lung disease

R Ma, TP Ortiz Serrano, J Davis, AD Prigge… - The FASEB …, 2020 - Wiley Online Library
The presence of DNA in the cytosol is usually a sign of microbial infections, which alerts the
host innate immune system to mount a defense response. Cyclic GMP‐AMP synthase …

[HTML][HTML] Chronic obstructive pulmonary disease (COPD) and lung cancer: common pathways for pathogenesis

BA Parris, HE O'Farrell, KM Fong… - Journal of thoracic …, 2019 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) and lung cancer comprise the leading
causes of lung disease-related mortality worldwide. Exposure to tobacco smoke is a mutual …

Lung function and incidence of chronic obstructive pulmonary disease after improved cooking fuels and kitchen ventilation: a 9-year prospective cohort study

Y Zhou, Y Zou, X Li, S Chen, Z Zhao, F He, W Zou… - PLoS …, 2014 - journals.plos.org
Background Biomass smoke is associated with the risk of chronic obstructive pulmonary
disease (COPD), but few studies have elaborated approaches to reduce the risk of COPD …

Airway inflammation in chronic obstructive pulmonary disease (COPD): a true paradox

MS Eapen, S Myers, EH Walters… - Expert review of …, 2017 - Taylor & Francis
Introduction: Chronic obstructive pulmonary disease (COPD) is primarily an airway
condition, which mainly affects cigarette smokers and presents with shortness of breath that …

DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease

J Birch, RK Anderson, C Correia-Melo… - … of Physiology-Lung …, 2015 - journals.physiology.org
Cellular senescence has been associated with the structural and functional decline
observed during physiological lung aging and in chronic obstructive pulmonary disease …

Reactive oxygen species, inflammation, and lung diseases

P Di Rosanna, C Salvatore - Current pharmaceutical design, 2012 - ingentaconnect.com
Reactive oxygen species (ROS) are well recognized for playing a dual role as both
deleterious and beneficial species. ROS are products of normal cellular metabolism and …