Aging and aging-related diseases: from molecular mechanisms to interventions and treatments
J Guo, X Huang, L Dou, M Yan, T Shen… - Signal Transduction and …, 2022 - nature.com
Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …
tissue and cell functions and significant increases in the risks of various aging-related …
Indoor air pollution, related human diseases, and recent trends in the control and improvement of indoor air quality
VV Tran, D Park, YC Lee - … journal of environmental research and public …, 2020 - mdpi.com
Indoor air pollution (IAP) is a serious threat to human health, causing millions of deaths each
year. A plethora of pollutants can result in IAP; therefore, it is very important to identify their …
year. A plethora of pollutants can result in IAP; therefore, it is very important to identify their …
The impact of ageing on monocytes and macrophages
RPH De Maeyer, ES Chambers - Immunology letters, 2021 - Elsevier
Ageing is a global burden. Increasing age is associated with increased incidence of
infections and cancer and decreased vaccine efficacy. This increased morbidity observed …
infections and cancer and decreased vaccine efficacy. This increased morbidity observed …
Mechanisms of lung damage and development of COPD due to household biomass-smoke exposure: inflammation, oxidative stress, MicroRNAs, and gene …
B Ortiz-Quintero, I Martínez-Espinosa, R Pérez-Padilla - Cells, 2022 - mdpi.com
Chronic exposure to indoor biomass smoke from the combustion of solid organic fuels is a
major cause of disease burden worldwide. Almost 3 billion people use solid fuels such as …
major cause of disease burden worldwide. Almost 3 billion people use solid fuels such as …
The cGAS‐STING pathway: the role of self‐DNA sensing in inflammatory lung disease
R Ma, TP Ortiz Serrano, J Davis, AD Prigge… - The FASEB …, 2020 - Wiley Online Library
The presence of DNA in the cytosol is usually a sign of microbial infections, which alerts the
host innate immune system to mount a defense response. Cyclic GMP‐AMP synthase …
host innate immune system to mount a defense response. Cyclic GMP‐AMP synthase …
[HTML][HTML] Chronic obstructive pulmonary disease (COPD) and lung cancer: common pathways for pathogenesis
BA Parris, HE O'Farrell, KM Fong… - Journal of thoracic …, 2019 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) and lung cancer comprise the leading
causes of lung disease-related mortality worldwide. Exposure to tobacco smoke is a mutual …
causes of lung disease-related mortality worldwide. Exposure to tobacco smoke is a mutual …
Lung function and incidence of chronic obstructive pulmonary disease after improved cooking fuels and kitchen ventilation: a 9-year prospective cohort study
Y Zhou, Y Zou, X Li, S Chen, Z Zhao, F He, W Zou… - PLoS …, 2014 - journals.plos.org
Background Biomass smoke is associated with the risk of chronic obstructive pulmonary
disease (COPD), but few studies have elaborated approaches to reduce the risk of COPD …
disease (COPD), but few studies have elaborated approaches to reduce the risk of COPD …
Airway inflammation in chronic obstructive pulmonary disease (COPD): a true paradox
MS Eapen, S Myers, EH Walters… - Expert review of …, 2017 - Taylor & Francis
Introduction: Chronic obstructive pulmonary disease (COPD) is primarily an airway
condition, which mainly affects cigarette smokers and presents with shortness of breath that …
condition, which mainly affects cigarette smokers and presents with shortness of breath that …
DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease
Cellular senescence has been associated with the structural and functional decline
observed during physiological lung aging and in chronic obstructive pulmonary disease …
observed during physiological lung aging and in chronic obstructive pulmonary disease …
Reactive oxygen species, inflammation, and lung diseases
P Di Rosanna, C Salvatore - Current pharmaceutical design, 2012 - ingentaconnect.com
Reactive oxygen species (ROS) are well recognized for playing a dual role as both
deleterious and beneficial species. ROS are products of normal cellular metabolism and …
deleterious and beneficial species. ROS are products of normal cellular metabolism and …