The rise of nonnegative matrix factorization: algorithms and applications

YT Guo, QQ Li, CS Liang - Information Systems, 2024 - Elsevier
Although nonnegative matrix factorization (NMF) is widely used, some matrix factorization
methods result in misleading results and waste of computing resources due to lack of timely …

Network learning for biomarker discovery

Y Ding, M Fu, P Luo, FX Wu - International Journal of Network Dynamics …, 2023 - sciltp.com
Everything is connected and thus networks are instrumental in not only modeling complex
systems with many components, but also accommodating knowledge about their …

DAESTB: inferring associations of small molecule–miRNA via a scalable tree boosting model based on deep autoencoder

L Peng, Y Tu, L Huang, Y Li, X Fu… - Briefings in …, 2022 - academic.oup.com
MicroRNAs (miRNAs) are closely related to a variety of human diseases, not only regulating
gene expression, but also having an important role in human life activities and being viable …

Benchmarking of computational methods for predicting circRNA-disease associations

W Lan, Y Dong, H Zhang, C Li, Q Chen… - Briefings in …, 2023 - academic.oup.com
Accumulating evidences demonstrate that circular RNA (circRNA) plays an important role in
human diseases. Identification of circRNA-disease associations can help for the diagnosis of …

Deciphering ligand–receptor-mediated intercellular communication based on ensemble deep learning and the joint scoring strategy from single-cell transcriptomic …

L Peng, J Tan, W Xiong, L Zhang, Z Wang… - Computers in Biology …, 2023 - Elsevier
Background: Cell–cell communication in a tumor microenvironment is vital to tumorigenesis,
tumor progression and therapy. Intercellular communication inference helps understand …

MPCLCDA: predicting circRNA–disease associations by using automatically selected meta-path and contrastive learning

W Liu, T Tang, X Lu, X Fu, Y Yang… - Briefings in …, 2023 - academic.oup.com
Circular RNA (circRNA) is closely associated with human diseases. Accordingly, identifying
the associations between human diseases and circRNA can help in disease prevention …

Predicting CircRNA-disease associations via feature convolution learning with heterogeneous graph attention network

L Peng, C Yang, Y Chen, W Liu - IEEE Journal of Biomedical …, 2023 - ieeexplore.ieee.org
Exploring the relationship between circular RNA (circRNA) and disease is beneficial for
revealing the mechanisms of disease pathogenesis. However, a blind search for all possible …

scDCCA: deep contrastive clustering for single-cell RNA-seq data based on auto-encoder network

J Wang, J Xia, H Wang, Y Su… - Briefings in …, 2023 - academic.oup.com
The advances in single-cell ribonucleic acid sequencing (scRNA-seq) allow researchers to
explore cellular heterogeneity and human diseases at cell resolution. Cell clustering is a …

Predicting lncRNA–disease associations based on combining selective similarity matrix fusion and bidirectional linear neighborhood label propagation

GB Xie, RB Chen, ZY Lin, GS Gu, JR Yu… - Briefings in …, 2023 - academic.oup.com
Recent studies have revealed that long noncoding RNAs (lncRNAs) are closely linked to
several human diseases, providing new opportunities for their use in detection and therapy …

A computational model of circRNA-associated diseases based on a graph neural network: prediction and case studies for follow-up experimental validation

M Niu, C Wang, Z Zhang, Q Zou - BMC biology, 2024 - Springer
Abstract Background Circular RNAs (circRNAs) have been confirmed to play a vital role in
the occurrence and development of diseases. Exploring the relationship between circRNAs …