Emerging droplet microfluidics

L Shang, Y Cheng, Y Zhao - Chemical reviews, 2017 - ACS Publications
Droplet microfluidics generates and manipulates discrete droplets through immiscible
multiphase flows inside microchannels. Due to its remarkable advantages, droplet …

Passive and active droplet generation with microfluidics: a review

P Zhu, L Wang - Lab on a Chip, 2017 - pubs.rsc.org
Precise and effective control of droplet generation is critical for applications of droplet
microfluidics ranging from materials synthesis to lab-on-a-chip systems. Methods for droplet …

The Poisson distribution and beyond: methods for microfluidic droplet production and single cell encapsulation

DJ Collins, A Neild, A DeMello, AQ Liu, Y Ai - Lab on a Chip, 2015 - pubs.rsc.org
There is a recognized and growing need for rapid and efficient cell assays, where the size of
microfluidic devices lend themselves to the manipulation of cellular populations down to the …

Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting

S Torino, M Dhurandhar, A Stroobants, R Claessens… - Nature …, 2023 - nature.com
Single-particle cryogenic electron microscopy (cryo-EM) allows reconstruction of high-
resolution structures of proteins in different conformations. Protein function often involves …

Active droplet generation in microfluidics

ZZ Chong, SH Tan, AM Gañán-Calvo, SB Tor, NH Loh… - Lab on a Chip, 2016 - pubs.rsc.org
The reliable generation of micron-sized droplets is an important process for various
applications in droplet-based microfluidics. The generated droplets work as a self-contained …

Functional TCR T cell screening using single-cell droplet microfluidics

AI Segaliny, G Li, L Kong, C Ren, X Chen, JK Wang… - Lab on a Chip, 2018 - pubs.rsc.org
Adoptive T cell transfer, in particular TCR T cell therapy, holds great promise for cancer
immunotherapy with encouraging clinical results. However, finding the right TCR T cell clone …

Photo-actuation of liquids for light-driven microfluidics: state of the art and perspectives

D Baigl - Lab on a Chip, 2012 - pubs.rsc.org
Using light to control liquid motion is a new paradigm for the actuation of microfluidic
systems. We review here the different principles and strategies to induce or control liquid …

Micro total analysis systems for cell biology and biochemical assays

ML Kovarik, PC Gach, DM Ornoff, Y Wang… - Analytical …, 2012 - ACS Publications
Novel applications of micro total analysis systems (μTAS) are addressing fundamental
biological questions, creating new biomedical reagents, and developing innovative cell and …

Magnetically actuated droplet manipulation and its potential biomedical applications

G Huang, M Li, Q Yang, Y Li, H Liu… - ACS applied materials …, 2017 - ACS Publications
Droplet manipulation has found broad applications in various engineering and biomedical
fields, such as biochemistry, microfluidic systems, drug delivery, and tissue engineering …

Droplet control technologies for microfluidic high throughput screening (μHTS)

M Sesen, T Alan, A Neild - Lab on a Chip, 2017 - pubs.rsc.org
The transition from micro well plate and robotics based high throughput screening (HTS) to
chip based screening has already started. This transition promises reduced droplet volumes …