With the increasing incidence of thoracic tumors, radiation therapy (RT) has become an
important component of comprehensive treatment. RT improves survival in many cancers …

The endothelium, a tissue that forms a single layer of cells lining various organs and cavities
of the body, especially the heart and blood as well as lymphatic vessels, plays a complex …

There is a distinct increase in the risk of heart disease in people exposed to ionizing
radiation (IR). Radiation‐induced heart disease (RIHD) is one of the adverse side effects …

Cardiovascular diseases are the most common causes of morbidity and mortality worldwide.
Redox dysregulation and a dyshomeostasis of inflammation arise from, and result in, cellular …

The interest in non-coding RNAs, which started more than a decade ago, has still not
weakened. A wealth of experimental and clinical studies has suggested the potential of non …

Radiation‐induced myocardial fibrosis (RIMF) is a potentially lethal clinical complication of
chest radiotherapy (RT) and a final stage of radiation‐induced heart disease (RIHD). RIMF is …

Radiotherapy plays an important role in the treatment of localized primary malignancies
involving the chest wall or intrathoracic malignancies. Secondary effects of radiotherapy on …

Opinion statement Cancer patients who receive high-dose thoracic radiotherapy may
develop radiation-induced heart disease (RIHD). The clinical presentation of RIHD …

H2 has been clinically demonstrated to provide antioxidant and anti-inflammatory effects,
which makes it an attractive agent in exercise medicine. Although exercise provides a …

Irradiation of normal tissues leads to acute increase in reactive oxygen/nitrogen species that
serve as intra-and inter-cellular signaling to alter cell and tissue function. In the case of chest …