Spinal cord repair: advances in biology and technology

G Courtine, MV Sofroniew - Nature medicine, 2019 - nature.com
Individuals with spinal cord injury (SCI) can face decades with permanent disabilities.
Advances in clinical management have decreased morbidity and improved outcomes, but …

Brain–computer interfaces for communication and rehabilitation

U Chaudhary, N Birbaumer… - Nature Reviews …, 2016 - nature.com
Brain–computer interfaces (BCIs) use brain activity to control external devices, thereby
enabling severely disabled patients to interact with the environment. A variety of invasive …

A high-performance speech neuroprosthesis

FR Willett, EM Kunz, C Fan, DT Avansino, GH Wilson… - Nature, 2023 - nature.com
Speech brain–computer interfaces (BCIs) have the potential to restore rapid communication
to people with paralysis by decoding neural activity evoked by attempted speech into text, or …

High-performance brain-to-text communication via handwriting

FR Willett, DT Avansino, LR Hochberg, JM Henderson… - Nature, 2021 - nature.com
Brain–computer interfaces (BCIs) can restore communication to people who have lost the
ability to move or speak. So far, a major focus of BCI research has been on restoring gross …

An accurate and rapidly calibrating speech neuroprosthesis

NS Card, M Wairagkar, C Iacobacci… - … England Journal of …, 2024 - Mass Medical Soc
Background Brain–computer interfaces can enable communication for people with paralysis
by transforming cortical activity associated with attempted speech into text on a computer …

Spelling interface using intracortical signals in a completely locked-in patient enabled via auditory neurofeedback training

U Chaudhary, I Vlachos, JB Zimmermann… - Nature …, 2022 - nature.com
Patients with amyotrophic lateral sclerosis (ALS) can lose all muscle-based routes of
communication as motor neuron degeneration progresses, and ultimately, they may be left …

Machine translation of cortical activity to text with an encoder–decoder framework

JG Makin, DA Moses, EF Chang - Nature neuroscience, 2020 - nature.com
A decade after speech was first decoded from human brain signals, accuracy and speed
remain far below that of natural speech. Here we show how to decode the …

High performance communication by people with paralysis using an intracortical brain-computer interface

C Pandarinath, P Nuyujukian, CH Blabe, BL Sorice… - elife, 2017 - elifesciences.org
Brain-computer interfaces (BCIs) have the potential to restore communication for people with
tetraplegia and anarthria by translating neural activity into control signals for assistive …

Home use of a percutaneous wireless intracortical brain-computer interface by individuals with tetraplegia

JD Simeral, T Hosman, J Saab… - IEEE Transactions …, 2021 - ieeexplore.ieee.org
Objective. Individuals with neurological disease or injury such as amyotrophic lateral
sclerosis, spinal cord injury or stroke may become tetraplegic, unable to speak or even …

Stabilization of a brain–computer interface via the alignment of low-dimensional spaces of neural activity

AD Degenhart, WE Bishop, ER Oby… - Nature biomedical …, 2020 - nature.com
The instability of neural recordings can render clinical brain–computer interfaces (BCIs)
uncontrollable. Here, we show that the alignment of low-dimensional neural manifolds (low …